ENSMUSG00000026356


Mus musculus

Features
Gene ID: ENSMUSG00000026356
  
Biological name :Dars
  
Synonyms : Aspartate--tRNA ligase, cytoplasmic / Dars / Q922B2
  
Possible biological names infered from orthology : aspartyl-tRNA synthetase / P14868
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: E3
Gene start: 128363707
Gene end: 128417368
  
Corresponding Affymetrix probe sets: 10357454 (MoGene1.0st)   1423800_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027602
Ensembl peptide - ENSMUSP00000066866
NCBI entrez gene - 226414     See in Manteia.
MGI - MGI:2442544
RefSeq - NM_177445
RefSeq - NM_145507
RefSeq Peptide - NP_663482
RefSeq Peptide - NP_803228
swissprot - Q8BJY7
swissprot - Q922B2
Ensembl - ENSMUSG00000026356
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 darsENSDARG00000070043Danio rerio
 DARSENSGALG00000012355Gallus gallus
 DARSENSG00000115866Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002312  Aspartyl/Asparaginyl-tRNA synthetase, class IIb
 IPR004364  Aminoacyl-tRNA synthetase, class II (D/K/N)
 IPR004365  OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
 IPR004523  Aspartate-tRNA synthetase, type 2
 IPR006195  Aminoacyl-tRNA synthetase, class II
 IPR012340  Nucleic acid-binding, OB-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006422 aspartyl-tRNA aminoacylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0017101 aminoacyl-tRNA synthetase multienzyme complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004815 aspartate-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptger4tm1.1Matb/Ptger4tm1.1Matb,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptger4tm1.1Matb/Ptger4tm1.1Matb,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Ptger4tm1.1Matb/Ptger4tm1.1Matb,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: 129S6/SvEvTac * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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