ENSMUSG00000026450


Mus musculus

Features
Gene ID: ENSMUSG00000026450
  
Biological name :Chit1
  
Synonyms : Chit1 / Chitotriosidase-1 / Q9D7Q1
  
Possible biological names infered from orthology : chitinase 1 / Q13231
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 134111242
Gene end: 134151540
  
Corresponding Affymetrix probe sets: 10349953 (MoGene1.0st)   1453844_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000083666
Ensembl peptide - ENSMUSP00000123979
Ensembl peptide - ENSMUSP00000124331
NCBI entrez gene - 71884     See in Manteia.
MGI - MGI:1919134
RefSeq - XM_006529881
RefSeq - NM_001284524
RefSeq - NM_001284525
RefSeq - NM_027979
RefSeq - XM_006529879
RefSeq - XM_006529880
RefSeq Peptide - NP_082255
RefSeq Peptide - NP_001271453
RefSeq Peptide - NP_001271454
swissprot - Q9D7Q1
swissprot - B2RS82
Ensembl - ENSMUSG00000026450
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CHIT1ENSG00000133063Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chia1 / Q91XA9 / Acidic mammalian chitinase / CHIA* / Q9BZP6* / chitinase, acidic*ENSMUSG0000006277848
Chil5 / chitinase-like 5 / CHIA* / Q9BZP6* / chitinase, acidic*ENSMUSG0000004387341
Ovgp1 / Q62010 / Oviduct-specific glycoprotein / Q12889* / oviductal glycoprotein 1*ENSMUSG0000007434041
Chil1 / Q61362 / Chitinase-3-like protein 1 / CHI3L1* / P36222* / chitinase 3 like 1*ENSMUSG0000006424640
Chil4 / Q91Z98 / Chitinase-like protein 4 / CHIA* / Q9BZP6* / chitinase, acidic*ENSMUSG0000006377939
Chil3 / O35744 / Chitinase-like protein 3 / CHIA* / Q9BZP6* / chitinase, acidic*ENSMUSG0000004080938
Chil6 / chitinase-like 6 / CHIA* / Q9BZP6* / chitinase, acidic*ENSMUSG0000002790237


Protein motifs (from Interpro)
Interpro ID Name
 IPR001223  Glycoside hydrolase family 18, catalytic domain
 IPR001579  Glycoside hydrolase, chitinase active site
 IPR002557  Chitin binding domain
 IPR011583  Chitinase II
 IPR017853  Glycoside hydrolase superfamily
 IPR029070  Chitinase insertion domain superfamily
 IPR036508  Chitin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000272 polysaccharide catabolic process IEA
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006030 chitin metabolic process IEA
 biological_processGO:0006032 chitin catabolic process ISO
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005576 extracellular region IBA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005764 lysosome IEA
 molecular_functionGO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA
 molecular_functionGO:0004568 chitinase activity IEA
 molecular_functionGO:0008061 chitin binding IBA
 molecular_functionGO:0008843 endochitinase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA


Pathways (from Reactome)
Pathway description
Digestion of dietary carbohydrate
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002411 decreased susceptibility to bacterial infection "reduced likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: ApcMin/ApcMin
Genetic Background: involves: C57BL/6J * CAST/EiJ

Allelic Composition: Chit1tm1Eli/Chit1tm1Eli,Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli/0
Genetic Background: involves: C57BL/6

Allelic Composition: Chit1tm1Eli/Chit1tm1Eli,Tg(Scgb1a1-Il13)2Eli/0
Genetic Background: involves: C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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