ENSMUSG00000026618


Mus musculus

Features
Gene ID: ENSMUSG00000026618
  
Biological name :Iars2
  
Synonyms : Iars2 / Isoleucine--tRNA ligase, mitochondrial / Q8BIJ6
  
Possible biological names infered from orthology : isoleucyl-tRNA synthetase 2, mitochondrial / Q9NSE4
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H5
Gene start: 185284726
Gene end: 185329396
  
Corresponding Affymetrix probe sets: 10360884 (MoGene1.0st)   1426735_at (Mouse Genome 430 2.0 Array)   1441665_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106601
Ensembl peptide - ENSMUSP00000106603
Ensembl peptide - ENSMUSP00000027921
NCBI entrez gene - 381314     See in Manteia.
MGI - MGI:1919586
RefSeq - XM_006497179
RefSeq - XM_006497180
RefSeq - NM_198653
RefSeq Peptide - NP_941055
swissprot - Q8BIJ6
swissprot - E9PWN3
swissprot - E9PWN2
Ensembl - ENSMUSG00000026618
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 iars2ENSDARG00000044134Danio rerio
 IARS2ENSGALG00000009566Gallus gallus
 IARS2ENSG00000067704Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001412  Aminoacyl-tRNA synthetase, class I, conserved site
 IPR002300  Aminoacyl-tRNA synthetase, class Ia
 IPR002301  Isoleucine-tRNA ligase
 IPR009008  Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
 IPR009080  Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
 IPR013155  Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR023585  Isoleucine-tRNA ligase, type 1
 IPR033708  Isoleucyl tRNA synthetase type 1, anticodon-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006428 isoleucyl-tRNA aminoacylation IEA
 biological_processGO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0002161 aminoacyl-tRNA editing activity IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004822 isoleucine-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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