ENSMUSG00000026697


Mus musculus

Features
Gene ID: ENSMUSG00000026697
  
Biological name :Myoc
  
Synonyms : Myoc / myocilin / O70624
  
Possible biological names infered from orthology : Q99972
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H2.1
Gene start: 162639155
Gene end: 162649693
  
Corresponding Affymetrix probe sets: 10351131 (MoGene1.0st)   1450468_at (Mouse Genome 430 2.0 Array)   1460306_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028020
NCBI entrez gene - 17926     See in Manteia.
MGI - MGI:1202864
RefSeq - NM_010865
RefSeq Peptide - NP_034995
swissprot - O70624
swissprot - Q05AC1
Ensembl - ENSMUSG00000026697
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myocENSDARG00000021789Danio rerio
 MYOCENSGALG00000021074Gallus gallus
 MYOCENSG00000034971Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Olfm1 / O88998 / olfactomedin 1 / Q99784*ENSMUSG0000002683330
Olfm3 / P63056 / olfactomedin 3 / Q96PB7*ENSMUSG0000002796529
Olfm2 / Q8BM13 / olfactomedin 2 / O95897*ENSMUSG0000003217228
Q3V1G4 / Olfml2b / Olfactomedin-like protein 2B / Q68BL8* / olfactomedin like 2B*ENSMUSG0000003846326
Q8BHP7 / Olfml2a / olfactomedin-like 2A / Q68BL7*ENSMUSG0000004661825
Olfm5 / olfactomedin 5ENSMUSG0000004426521
Olfm4 / Q3UZZ4 / Mus musculus olfactomedin 4 (Olfm4), mRNA. / Q6UX06* / olfactomedin 4*ENSMUSG0000002202620
Olfml3 / olfactomedin like 3 / Q9NRN5*ENSMUSG0000002784817
Gldn / Q8BMF8 / Gliomedin Gliomedin shedded ectodomain / Q6ZMI3* / gliomedin*ENSMUSG0000004616716
Olfml1 / olfactomedin-like 1 / Q6UWY5*ENSMUSG000000510417


Protein motifs (from Interpro)
Interpro ID Name
 IPR003112  Olfactomedin-like domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR031213  Myocilin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0001952 regulation of cell-matrix adhesion IEA
 biological_processGO:0001953 negative regulation of cell-matrix adhesion IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0014734 skeletal muscle hypertrophy IDA
 biological_processGO:0022011 myelination in peripheral nervous system IMP
 biological_processGO:0030335 positive regulation of cell migration ISS
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0035024 negative regulation of Rho protein signal transduction IEA
 biological_processGO:0038031 non-canonical Wnt signaling pathway via JNK cascade IEA
 biological_processGO:0038133 ERBB2-ERBB3 signaling pathway IDA
 biological_processGO:0043408 regulation of MAPK cascade IEA
 biological_processGO:0045162 clustering of voltage-gated sodium channels IMP
 biological_processGO:0051492 regulation of stress fiber assembly IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0051497 negative regulation of stress fiber assembly IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0051901 positive regulation of mitochondrial depolarization IEA
 biological_processGO:0060348 bone development IDA
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0005743 mitochondrial inner membrane ISO
 cellular_componentGO:0005758 mitochondrial intermembrane space ISO
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005791 rough endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 cellular_componentGO:0033268 node of Ranvier IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome ISS
 molecular_functionGO:0001968 fibronectin binding IEA
 molecular_functionGO:0005109 frizzled binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030971 receptor tyrosine kinase binding IPI
 molecular_functionGO:0032027 myosin light chain binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bbs4Gt1Nk/Bbs4Gt1Nk
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0005257 abnormal intraocular pressure "anomaly in the amount of force per unit area exerted by the intraocular fluid within the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ybx1tm1Ley/Ybx1tm1Ley
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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