ENSMUSG00000026709


Mus musculus

Features
Gene ID: ENSMUSG00000026709
  
Biological name :Dars2
  
Synonyms : Aspartate--tRNA ligase, mitochondrial / Dars2 / Q8BIP0
  
Possible biological names infered from orthology : aspartyl-tRNA synthetase 2, mitochondrial / Q6PI48
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H2.1
Gene start: 161040601
Gene end: 161070658
  
Corresponding Affymetrix probe sets: 10359386 (MoGene1.0st)   1433838_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041851
NCBI entrez gene - 226539     See in Manteia.
MGI - MGI:2442510
RefSeq - XM_006496758
RefSeq - NM_172644
RefSeq - XM_006496757
RefSeq Peptide - NP_766232
swissprot - Q8BIP0
Ensembl - ENSMUSG00000026709
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dars2ENSDARG00000060861Danio rerio
 DARS2ENSGALG00000023749Gallus gallus
 DARS2ENSG00000117593Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002312  Aspartyl/Asparaginyl-tRNA synthetase, class IIb
 IPR004115  GAD-like domain superfamily
 IPR004364  Aminoacyl-tRNA synthetase, class II (D/K/N)
 IPR004365  OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
 IPR004524  Aspartate-tRNA ligase, type 1
 IPR006195  Aminoacyl-tRNA synthetase, class II
 IPR012340  Nucleic acid-binding, OB-fold
 IPR029351  GAD domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0043039 tRNA aminoacylation IEA
 biological_processGO:0070145 mitochondrial asparaginyl-tRNA aminoacylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005759 mitochondrial matrix IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004815 aspartate-tRNA ligase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0050560 aspartate-tRNA(Asn) ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cptm1b(KOMP)Wtsi/Cptm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Cptm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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