ENSMUSG00000026972


Mus musculus

Features
Gene ID: ENSMUSG00000026972
  
Biological name :Arrdc1
  
Synonyms : Arrdc1 / Arrestin domain-containing protein 1 / Q99KN1
  
Possible biological names infered from orthology : arrestin domain containing 1 / Q8N5I2
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A3
Gene start: 24925352
Gene end: 24935252
  
Corresponding Affymetrix probe sets: 10480570 (MoGene1.0st)   1424578_at (Mouse Genome 430 2.0 Array)   1444508_s_at (Mouse Genome 430 2.0 Array)   1458613_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028349
Ensembl peptide - ENSMUSP00000116352
Ensembl peptide - ENSMUSP00000117695
Ensembl peptide - ENSMUSP00000117372
Ensembl peptide - ENSMUSP00000099999
Ensembl peptide - ENSMUSP00000114684
NCBI entrez gene - 215705     See in Manteia.
MGI - MGI:2446136
RefSeq - XM_006497839
RefSeq - XM_006497838
RefSeq - XM_006497841
RefSeq - XM_006497840
RefSeq - NM_001162485
RefSeq - NM_178408
RefSeq - XM_006497842
RefSeq Peptide - NP_848495
RefSeq Peptide - NP_001155957
swissprot - Q99KN1
swissprot - D6RDR8
swissprot - A2AIS9
swissprot - F7ANZ2
swissprot - F6Q4G2
Ensembl - ENSMUSG00000026972
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arrdc1aENSDARG00000068148Danio rerio
 arrdc1bENSDARG00000079839Danio rerio
 ARRDC1ENSGALG00000008475Gallus gallus
 ARRDC1ENSG00000197070Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arrdc4 / A0A0B4J1F4 / Arrestin domain-containing protein 4 / Q8NCT1* / arrestin domain containing 4*ENSMUSG0000004265923
Arrdc2 / Q9D668 / Arrestin domain-containing protein 2 / Q8TBH0* / arrestin domain containing 2*ENSMUSG0000000291023
Arrdc3 / Q7TPQ9 / Arrestin domain-containing protein 3 / Q96B67* / arrestin domain containing 3*ENSMUSG0000007479421
Txnip / Q8BG60 / thioredoxin interacting protein / Q9H3M7*ENSMUSG0000003839319


Protein motifs (from Interpro)
Interpro ID Name
 IPR011021  Arrestin-like, N-terminal
 IPR011022  Arrestin C-terminal-like domain
 IPR014756  Immunoglobulin E-set


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006858 extracellular transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IEA
 biological_processGO:0140112 extracellular vesicle biogenesis IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:1903561 extracellular vesicle IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination IEA
 molecular_functionGO:1990763 arrestin family protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ccna2tm1Sot/Ccna2tm1Sot
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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