ENSMUSG00000026980


Mus musculus

Features
Gene ID: ENSMUSG00000026980
  
Biological name :Ly75
  
Synonyms : Ly75 / Lymphocyte antigen 75 / Q60767
  
Possible biological names infered from orthology : LY75-CD302 / LY75-CD302 readthrough / O60449
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: C1.1
Gene start: 60292103
Gene end: 60383303
  
Corresponding Affymetrix probe sets: 10482929 (MoGene1.0st)   1449328_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108152
Ensembl peptide - ENSMUSP00000028362
NCBI entrez gene - 17076     See in Manteia.
MGI - MGI:106662
RefSeq - NM_013825
RefSeq Peptide - NP_038853
swissprot - A2AW86
swissprot - Q60767
Ensembl - ENSMUSG00000026980
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ly75ENSDARG00000053113Danio rerio
 LY75ENSGALG00000011153Gallus gallus
 LY75ENSG00000054219Homo sapiens
 LY75-CD302ENSG00000248672Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pla2r1 / Q62028 / Secretory phospholipase A2 receptor Soluble secretory phospholipase A2 receptor / Q13018* / phospholipase A2 receptor 1*ENSMUSG0000005458027
Mrc2 / Q64449 / C-type mannose receptor 2 / Q9UBG0* / mannose receptor C type 2*ENSMUSG0000002069526
Mrc1 / Q61830 / mannose receptor, C type 1 / P22897*ENSMUSG0000002671222


Protein motifs (from Interpro)
Interpro ID Name
 IPR000562  Fibronectin type II domain
 IPR000772  Ricin B, lectin domain
 IPR001304  C-type lectin-like
 IPR013806  Kringle-like fold
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR035992  Ricin B-like lectins
 IPR036943  Fibronectin type II domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005010 abnormal CD8+ T cell morphology/development "anomalous structure, formation, or numbers of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Grm1tm1Crpl/Grm1tm1Crpl
Genetic Background: Not Specified

 MP:0005078 abnormal cytotoxic T cell physiology "impaired function of the subset of CD8+ T lymphocytes capable of directly killing appropriately targeted cells " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Grm1tm1Crpl/Grm1tm1Crpl
Genetic Background: Not Specified

 MP:0009763 increased sensitivity to induced morbidity/mortality "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Atoh7tm1Gla/Atoh7tm1Gla,Tg(Crx-Atoh7,-cre)251Gla/0,Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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