ENSMUSG00000026985


Mus musculus

Features
Gene ID: ENSMUSG00000026985
  
Biological name :Il1f8
  
Synonyms : Il1f8 / Interleukin-36 beta / Q9D6Z6
  
Possible biological names infered from orthology : IL36B / Q9NZH7
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: A3
Gene start: 24153161
Gene end: 24160519
  
Corresponding Affymetrix probe sets: 10469774 (MoGene1.0st)   1425715_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028363
NCBI entrez gene - 69677     See in Manteia.
MGI - MGI:1916927
RefSeq - NM_027163
RefSeq Peptide - NP_081439
swissprot - Q08EA6
swissprot - Q9D6Z6
Ensembl - ENSMUSG00000026985
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL36BENSG00000136696Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Il1f9 / IL36G* / Q9NZH8* / interleukin 36 gamma*ENSMUSG0000004410333
Il1f6 / Q9JLA2 / interleukin 1 family, member 6 / IL36A* / Q9UHA7* / interleukin 36 alpha*ENSMUSG0000002698428


Protein motifs (from Interpro)
Interpro ID Name
 IPR000975  Interleukin-1 family
 IPR008996  Cytokine IL1/FGF
 IPR020877  Interleukin-1 conserved site
 IPR027172  Interleukin-36 beta


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001819 positive regulation of cytokine production IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0032755 positive regulation of interleukin-6 production IGI
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045582 positive regulation of T cell differentiation IGI
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0005125 cytokine activity IGI
 molecular_functionGO:0005149 interleukin-1 receptor binding IBA


Pathways (from Reactome)
Pathway description
Interleukin-36 pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022514 Il1rap / Q61730 / Interleukin-1 receptor accessory protein / Q9NPH3*  / complex / reaction
 ENSMUSG00000070942 Il1rl2 / Q9ERS7 / Mus musculus interleukin 1 receptor-like 2 (Il1rl2), transcript variant 2, mRNA. / Q9HB29* / interleukin 1 receptor like 2*  / complex / reaction






 

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