ENSMUSG00000027015


Mus musculus

Features
Gene ID: ENSMUSG00000027015
  
Biological name :Cybrd1
  
Synonyms : Cybrd1 / Cytochrome b reductase 1 / Q925G2
  
Possible biological names infered from orthology : Q53TN4
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C2
Gene start: 71117923
Gene end: 71142926
  
Corresponding Affymetrix probe sets: 10472757 (MoGene1.0st)   1425040_at (Mouse Genome 430 2.0 Array)   1460604_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028403
NCBI entrez gene - 73649     See in Manteia.
MGI - MGI:2654575
RefSeq - NM_028593
RefSeq Peptide - NP_082869
swissprot - Q925G2
Ensembl - ENSMUSG00000027015
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cybrd1ENSDARG00000095577Danio rerio
 CYBRD1ENSGALG00000030703Gallus gallus
 CYBRD1ENSG00000071967Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6P1H1 / Cyb561a3 / Cytochrome b ascorbate-dependent protein 3 / Q8NBI2* / cytochrome b561 family member A3*ENSMUSG0000003444533
Cyb561 / Q60720 / Cytochrome b561 / P49447*ENSMUSG0000001959030


Protein motifs (from Interpro)
Interpro ID Name
 IPR006593  Cytochrome b561/ferric reductase transmembrane
 IPR028838  Cytochrome b reductase 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010039 response to iron ion IDA
 biological_processGO:0055114 oxidation-reduction process IBA
 cellular_componentGO:0005765 lysosomal membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031526 brush border membrane IDA
 molecular_functionGO:0000293 ferric-chelate reductase activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002834 decreased heart weight "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
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Allelic Composition: Cyb561tm1b(EUCOMM)Wtsi/Cyb561tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cyb561tm1b(EUCOMM)Wtsi/H

 MP:0002981 increased liver weight "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]
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Allelic Composition: Anpeptm1Sid/Anpep+
Genetic Background: involves: 129S/SvEv * C57BL/6

 MP:0008743 decreased liver iron level "reduction in the amount of iron present in the liver tissue" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Anpeptm1Sid/Anpep+
Genetic Background: involves: 129S/SvEv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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