ENSMUSG00000034445


Mus musculus

Features
Gene ID: ENSMUSG00000034445
  
Biological name :Cyb561a3
  
Synonyms : Cyb561a3 / Cytochrome b ascorbate-dependent protein 3 / Q6P1H1
  
Possible biological names infered from orthology : cytochrome b561 family member A3 / Q8NBI2
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 10577454
Gene end: 10588548
  
Corresponding Affymetrix probe sets: 10461487 (MoGene1.0st)   1434245_a_at (Mouse Genome 430 2.0 Array)   1447244_at (Mouse Genome 430 2.0 Array)   1454895_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130680
NCBI entrez gene - 225912     See in Manteia.
MGI - MGI:2686925
RefSeq - NM_001282067
RefSeq - NM_201351
RefSeq - XM_017318151
RefSeq - NM_001282064
RefSeq - NM_001282065
RefSeq - XM_006526940
RefSeq - XM_017318147
RefSeq - XM_017318148
RefSeq - XM_017318149
RefSeq - XM_017318150
RefSeq - XM_006526935
RefSeq - XM_006526937
RefSeq - XM_006526938
RefSeq - XM_006526939
RefSeq Peptide - NP_001268994
RefSeq Peptide - NP_001268996
RefSeq Peptide - NP_958739
RefSeq Peptide - NP_001268993
swissprot - Q6P1H1
Ensembl - ENSMUSG00000034445
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A3KPR5ENSDARG00000056281Danio rerio
 cyb561a3bENSDARG00000028257Danio rerio
 CYB561A3ENSGALG00000032051Gallus gallus
 Q8NBI2ENSG00000162144Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyb561 / Q60720 / Cytochrome b561 / P49447*ENSMUSG0000001959040
Cybrd1 / Q925G2 / Cytochrome b reductase 1 / Q53TN4*ENSMUSG0000002701539


Protein motifs (from Interpro)
Interpro ID Name
 IPR006593  Cytochrome b561/ferric reductase transmembrane
 IPR028836  Cytochrome b ascorbate-dependent protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IBA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005765 lysosomal membrane IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane IDA
 molecular_functionGO:0016491 oxidoreductase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005627 increased circulating potassium level "greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0010068 decreased red blood cell distribution width "lower than normal coefficient of variance (reference range) of the red blood cell volume for an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", NCI:C64800 "NCI Thesaurus (Code C64800)"]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0013279 increased fasted circulating glucose level "increase in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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