ENSMUSG00000027406


Mus musculus

Features
Gene ID: ENSMUSG00000027406
  
Biological name :Idh3b
  
Synonyms : Idh3b / isocitrate dehydrogenase 3 (NAD(+)) beta
  
Possible biological names infered from orthology : O43837
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: F1
Gene start: 130279309
Gene end: 130284547
  
Corresponding Affymetrix probe sets: 10487629 (MoGene1.0st)   1418885_a_at (Mouse Genome 430 2.0 Array)   1418886_s_at (Mouse Genome 430 2.0 Array)   1441271_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028892
Ensembl peptide - ENSMUSP00000139331
NCBI entrez gene - 170718     See in Manteia.
MGI - MGI:2158650
RefSeq - XM_006498824
RefSeq - NM_130884
RefSeq Peptide - NP_570954
swissprot - Q91VA7
swissprot - V9GXV0
Ensembl - ENSMUSG00000027406
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 idh3bENSDARG00000044753Danio rerio
 IDH3BENSG00000101365Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Idh3g / P70404 / isocitrate dehydrogenase 3 (NAD+), gamma / P51553*ENSMUSG0000000201049
Q8BPC6 / 4933405O20Rik / Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial ENSMUSG0000008423444


Protein motifs (from Interpro)
Interpro ID Name
 IPR004434  Isocitrate dehydrogenase NAD-dependent
 IPR019818  Isocitrate/isopropylmalate dehydrogenase, conserved site
 IPR024084  Isopropylmalate dehydrogenase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006102 isocitrate metabolic process IEA
 biological_processGO:0006103 2-oxoglutarate metabolic process IEA
 biological_processGO:0006734 NADH metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004449 isocitrate dehydrogenase (NAD+) activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032279 Idh3a / Q9D6R2 / Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial / P50213* / isocitrate dehydrogenase 3 (NAD(+)) alpha*  / complex
 ENSMUSG00000002010 Idh3g / P70404 / isocitrate dehydrogenase 3 (NAD+), gamma / P51553*  / complex






 

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