ENSMUSG00000032279


Mus musculus

Features
Gene ID: ENSMUSG00000032279
  
Biological name :Idh3a
  
Synonyms : Idh3a / Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial / Q9D6R2
  
Possible biological names infered from orthology : isocitrate dehydrogenase 3 (NAD(+)) alpha / P50213
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A5.3
Gene start: 54586334
Gene end: 54604661
  
Corresponding Affymetrix probe sets: 10585417 (MoGene1.0st)   1422500_at (Mouse Genome 430 2.0 Array)   1422501_s_at (Mouse Genome 430 2.0 Array)   1432016_a_at (Mouse Genome 430 2.0 Array)   1447701_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127526
Ensembl peptide - ENSMUSP00000150296
Ensembl peptide - ENSMUSP00000149036
NCBI entrez gene - 67834     See in Manteia.
MGI - MGI:1915084
RefSeq - NM_029573
RefSeq Peptide - NP_083849
swissprot - A0A1L1STE6
swissprot - A0A1L1SQF9
swissprot - Q9D6R2
Ensembl - ENSMUSG00000032279
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 idh3aENSDARG00000030278Danio rerio
 IDH3AENSGALG00000037401Gallus gallus
 IDH3AENSG00000166411Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004434  Isocitrate dehydrogenase NAD-dependent
 IPR019818  Isocitrate/isopropylmalate dehydrogenase, conserved site
 IPR024084  Isopropylmalate dehydrogenase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0043209 myelin sheath IDA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0004449 isocitrate dehydrogenase (NAD+) activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001326 retinal degeneration "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Hexbmpc191H/Hexbmpc191H
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

 MP:0006149 blurred vision "loss of visiual acuity or ability to distinguish small details" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Hexbmpc191H/Hexbmpc191H
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027406 Idh3b / isocitrate dehydrogenase 3 (NAD(+)) beta / O43837*  / complex
 ENSMUSG00000002010 Idh3g / P70404 / isocitrate dehydrogenase 3 (NAD+), gamma / P51553*  / complex
 ENSMUSG00000032279 Idh3a / Q9D6R2 / Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial / P50213* / isocitrate dehydrogenase 3 (NAD(+)) alpha*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr