ENSDARG00000030278


Danio rerio

Features
Gene ID: ENSDARG00000030278
  
Biological name :idh3a
  
Synonyms : idh3a / isocitrate dehydrogenase 3 (NAD+) alpha
  
Possible biological names infered from orthology : Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial / P50213 / Q9D6R2
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 25766033
Gene end: 25829109
  
Corresponding Affymetrix probe sets: Dr.13580.1.S1_at (Zebrafish Array)   NM_200951_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000039951
Ensembl peptide - ENSDARP00000094415
NCBI entrez gene - 393926     See in Manteia.
RefSeq - NM_200951
RefSeq Peptide - NP_957245
swissprot - F1QI80
swissprot - Q6NV33
ZFIN ID - ZDB-GENE-040426-1007
Ensembl - ENSDARG00000030278
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IDH3AENSGALG00000037401Gallus gallus
 IDH3AENSG00000166411Homo sapiens
 Idh3aENSMUSG00000032279Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004434  Isocitrate dehydrogenase NAD-dependent
 IPR019818  Isocitrate/isopropylmalate dehydrogenase, conserved site
 IPR024084  Isopropylmalate dehydrogenase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004449 isocitrate dehydrogenase (NAD+) activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000044753 idh3b / isocitrate dehydrogenase 3 (NAD+) beta / O43837*  / complex
 ENSDARG00000030278 idh3a / isocitrate dehydrogenase 3 (NAD+) alpha / P50213* / Q9D6R2* / Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial *  / complex
 ENSDARG00000023648 idh3g / isocitrate dehydrogenase 3 (NAD+) gamma / Q8BPC6* / P51553* / P70404* / 4933405O20Rik* / Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial *  / complex






 

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contact: otassy@igbmc.fr