ENSMUSG00000027412


Mus musculus

Features
Gene ID: ENSMUSG00000027412
  
Biological name :Lpin3
  
Synonyms : Lpin3 / Phosphatidate phosphatase LPIN3 / Q99PI4
  
Possible biological names infered from orthology : lipin 3 / Q9BQK8
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H2
Gene start: 160880670
Gene end: 160906002
  
Corresponding Affymetrix probe sets: 10478258 (MoGene1.0st)   1449440_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105082
Ensembl peptide - ENSMUSP00000105083
Ensembl peptide - ENSMUSP00000043053
Ensembl peptide - ENSMUSP00000105081
NCBI entrez gene - 64899     See in Manteia.
MGI - MGI:1891342
RefSeq - NM_001199118
RefSeq - NM_022883
RefSeq Peptide - NP_001186047
RefSeq Peptide - NP_075021
swissprot - Q99PI4
swissprot - A2A4B1
swissprot - Q149B0
swissprot - A2A4B3
Ensembl - ENSMUSG00000027412
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:123305ENSDARG00000015563Danio rerio
 LPIN3ENSG00000132793Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lpin2 / Q99PI5 / Mus musculus lipin 2 (Lpin2), transcript variant 3, mRNA. / Q92539* / lipin 2*ENSMUSG0000002405245
Lpin1 / Mus musculus lipin 1 (Lpin1), transcript variant 4, mRNA. / Q14693* / lipin 1*ENSMUSG0000002059344


Protein motifs (from Interpro)
Interpro ID Name
 IPR007651  Lipin, N-terminal
 IPR013209  Lipin/Ned1/Smp2 (LNS2)
 IPR023214  HAD superfamily
 IPR031315  LNS2/PITP
 IPR031703  Lipin, middle domain
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0009062 fatty acid catabolic process IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0019432 triglyceride biosynthetic process IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003713 transcription coactivator activity IBA
 molecular_functionGO:0008195 phosphatidate phosphatase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PC
Synthesis of PE
Depolymerisation of the Nuclear Lamina
Triglyceride biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000220 increased monocyte count "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

 MP:0001529 abnormal vocalization "an inability, decreased ability or altered ability to produce sound from the vocal organs; or a general increase or decrease in the production of vocal sound" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:85479]
Show

Allelic Composition: Izumo1rtm2a(KOMP)Wtsi/Izumo1rtm2a(KOMP)Wtsi
Genetic Background: C57BL/6N-Izumo1rtm2a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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