MP:0000183 | decreased circulating LDL cholesterol level | "less than average concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
|
MP:0000187 | abnormal triglyceride level | "anomalous concentration of this molecule, glycerol esterified at each of its three hydroxyl groups by a fatty acid; triglyceride is an important molecule for storage of fatty acids in adipose tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
|
MP:0000272 | abnormal aorta morphology | "structural anomaly of the main trunk of the systemic arteries" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0000420 | ruffled hair | "fuzzy, irregular appearance of the hair" [J:50844] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0000424 | retarded hair growth | "slow growth of the hair, appears at normal time" [J:5476] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
|
MP:0000599 | enlarged liver | "larger than average size of the liver" [J:65146] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
|
MP:0000603 | pale liver | "liver lacking normal coloration, often refers to bloodless condition" [J:18048] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
|
MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
|
MP:0000754 | partial paralysis | "partial loss of power of voluntary movement in a muscle through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin1fld/Lpin1fld,Nrcam20884/Nrcam20884 Genetic Background: involves: BALB/cByJ * C57BL/6J
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MP:0000755 | hindlimb paralysis | "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin1fld/Lpin1fld,Nrcam20884/Nrcam20884 Genetic Background: involves: BALB/cByJ * C57BL/6J
|
MP:0000920 | abnormal myelination | "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
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MP:0000921 | demyelination | "loss of the myelin sheath without loss of axons or fiber tracts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lpin1tm1Rchr/Lpin1tm1Rchr,Tg(Mpz-cre)26Mes/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin120884 Genetic Background: involves: C57BL/6J
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MP:0000958 | peripheral nervous system degeneration | "a retrogressive impairment of function or destruction of the ganglia and peripheral nerves that lie outside the brain and spinal cord" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
|
MP:0001105 | abnormal PNS glia | "malformation or absence of non-neuronal cells that form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0001106 | abnormal Schwann cell | "malformed or absent cells which form the insulating myelin sheaths of peripheral axons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1tm1Rchr/Lpin1tm1Rchr,Tg(Mpz-cre)26Mes/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
|
MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tsg101tm1Kuw/Tsg101tm1Kuw,Tg(Wap-cre)11738Mam/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0001382 | abnormal nursing | "females do not nurse pups or nurse pups infrequently" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
|
MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1tm1Rchr/Lpin1tm1Rchr,Tg(Mpz-cre)26Mes/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin120884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin1fld Genetic Background: involves: BALB/cByJ * C57BL/6J
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MP:0001511 | disheveled coat | "coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0001513 | limb grasping | "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1tm1Rchr/Lpin1tm1Rchr,Tg(Mpz-cre)26Mes/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin1fld Genetic Background: involves: BALB/cByJ * C57BL/6J
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MP:0001516 | abnormal motor coordination/ balance | "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tsg101tm1Kuw/Tsg101tm1Kuw,Tg(Wap-cre)11738Mam/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0001524 | impaired limb coordination | "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0001547 | abnormal lipid level | "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0001552 | increased circulating triglyceride level | "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0001556 | increased circulating HDL cholesterol level | "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
Show
Allelic Composition: Thrbtm3.1Df/Thrbtm3.1Df Genetic Background: B6J.Cg-Thrbtm3.1Df
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin120884/Lpin1fld Genetic Background: involves: BALB/cByJ * C57BL/6J
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
|
MP:0002073 | abnormal hair growth | "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tsg101tm1Kuw/Tsg101tm1Kuw,Tg(Wap-cre)11738Mam/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0002078 | abnormal glucose homeostasis | "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
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MP:0002079 | increased circulating insulin level | "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
|
MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tsg101tm1Kuw/Tsg101tm1Kuw,Tg(Wap-cre)11738Mam/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0002118 | abnormal lipid homeostasis | "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tsg101tm1Kuw/Tsg101tm1Kuw,Tg(Wap-cre)11738Mam/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0002272 | abnormal nervous system electrophysiology | "anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Lpin1tm1Rchr/Lpin1tm1Rchr,Tg(Mpz-cre)26Mes/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
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MP:0002566 | abnormal sexual interaction | "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: a16H/a16H Genetic Background: involves: 101/H * C3H/HeH
|
MP:0002628 | fatty liver | "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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MP:0002651 | abnormal sciatic nerve | "malformation, absence or misprojection of the nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1tm1Rchr/Lpin1tm1Rchr,Tg(Mpz-cre)26Mes/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin120884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin1fld Genetic Background: involves: BALB/cByJ * C57BL/6J
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MP:0002925 | abnormal cardiovascular development | "aberrant formation or incomplete differentiation of the cardiovascular system" [RGD:Rat Genome Database submission] |
Show
Allelic Composition: Thrbtm3.1Df/Thrbtm3.1Df Genetic Background: B6J.Cg-Thrbtm3.1Df
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MP:0002971 | abnormal brown fat morphology | "defect in the thermogenic form of adipose tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0003059 | decreased insulin secretion | "less than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0003383 | abnormal gluconeogenesis | "anomaly in the formation of glucose from noncarbohydrates, such as proteins or fat" [J:93896] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
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MP:0003871 | abnormal myelin sheath morphology | "malformation of the insulating envelope that surrounds nerve fibers or axons" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin120884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin1fld Genetic Background: involves: BALB/cByJ * C57BL/6J
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MP:0003961 | decreased lean body mass | "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0003975 | increased circulating VLDL triglyceride level | "higher than average concentration in the blood of very low density lipoprotein, which normally transports triglycerides from the intestine and liver to muscle and adipose tissue" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0003982 | increased cholesterol level | "greater than normal concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0003984 | embryonic growth retardation | "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Thrbtm3.1Df/Thrbtm3.1Df Genetic Background: B6J.Cg-Thrbtm3.1Df
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MP:0004129 | abnormal respiratory quotient | "anomaly in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism" [J:94416] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
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MP:0004777 | abnormal phospholipid level | "anomalous concentration of the fat derivatives in which one fatty acid has been replaced by a phosphate group" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
|
MP:0005146 | decreased circulating VLDL cholesterol level | "less than average concentration in the blood of very low density lipoprotein, which normally transports triglycerides from the intestine and liver to muscle and adipose tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0005266 | abnormal metabolism | "anomalous chemical and physical changes occurring in tissue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
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MP:0005278 | abnormal cholesterol homeostasis | "anomaly in the state of equilibrium in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:71350] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0005281 | increased fatty acid level | "higher than normal non-circulating level of organic, monobasic acids derived from hydrocarbons; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0005282 | decreased fatty acid level | "less than normal non-circulating level of organic, monobasic acids derived from hydrocarbons; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0005293 | impaired glucose tolerance | "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0005317 | increased triglyceride level | "higher than normal concentration of triacylglycerols " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
|
MP:0005318 | decreased triglyceride level | "lower than normal concentration of triacylglycerols " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0005319 | abnormal enzyme/ coenzyme level | "altered concentration of any of these proteins, or their cofactors, that act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
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MP:0005331 | insulin resistance | "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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MP:0005402 | abnormal action potential | "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
Allelic Composition: Lpin1tm1Rchr/Lpin1tm1Rchr,Tg(Mpz-cre)26Mes/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin120884 Genetic Background: involves: C57BL/6J
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MP:0005404 | abnormal axon morphology | "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0005405 | axon degeneration | "retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0005440 | increased glycogen level | "greater than the normal concentration of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
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MP:0005559 | increased circulating glucose level | "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
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MP:0005584 | abnormal enzyme/coenzyme activity | "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0005668 | decreased circulating leptin level | "less than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751] |
Show
Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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MP:0005670 | abnormal white fat physiology | "functional aberration in the connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
|
MP:0006319 | abnormal epididymal fat pad | "any structural anomaly of the encapsulated adipose tissue associated with the epididymis" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0006379 | abnormal spermatocyte morphology | "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Phc2tm1Hko/Phc2tm1Hko Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0008069 | abnormal joint mobility | "anomaly in the ability to move joints in a full range of motion and with ease" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin120884 Genetic Background: involves: C57BL/6J
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MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0008814 | reduced nerve conduction velocity | "decrease in the rate at which an eletrical impulse travels through a nerve" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Grid2Lc/Grid2+ Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J
Allelic Composition: Lpin1tm1Rchr/Lpin1tm1Rchr,Tg(Mpz-cre)26Mes/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin120884/Lpin120884 Genetic Background: involves: C57BL/6J
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MP:0008976 | delayed female fertility | "ability of a female organism to produce live offspring occurring at a later than expected age" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0009115 | abnormal fat cell morphology | "any structural anomaly of a fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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MP:0009122 | decreased white fat cell lipid droplet size | "reduction in the size of the single large lipid droplet or vacuole of white fat cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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MP:0009125 | decreased brown fat cell lipid droplet size | "reduction in the size of the multiple small droplets of triglycerides found in brown adipocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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MP:0009289 | decreased epididymal fat pad weight | |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0009293 | decreased inguinal fat pad weight | |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0009295 | decreased interscapular fat pad weight | |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0009355 | increased liver triglyceride level | "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0009413 | skeletal muscle fiber atrophy | "a wasting of skeletal muscle fibers resulting in a derangement of the skeletal muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
Allelic Composition: Lpin1fld/Lpin1fld,Nrcam20884/Nrcam20884 Genetic Background: involves: BALB/cByJ * C57BL/6J
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MP:0010052 | increased grip strength | "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
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Allelic Composition: Lpin120884/Lpin120884 Genetic Background: involves: C57BL/6J
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MP:0010053 | decreased grip strength | "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
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Allelic Composition: Lpin120884/Lpin120884,Nrcam20884/Nrcam20884 Genetic Background: involves: C57BL/6J
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MP:0011084 | partial lethality at weaning | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms at weaning age" [MGI:csmith] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Thrbtm3.1Df/Thrbtm3.1Df Genetic Background: B6J.Cg-Thrbtm3.1Df
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MP:0011579 | decreased lipoprotein lipase activity | "reduced ability to catalyze the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate" [GO:0004465] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0011582 | decreased triglyceride lipase activity | "reduced ability to catalyze the reaction: triacylglycerol + H2O = diacylglycerol + a fatty acid anion" [GO:0004806] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0011591 | decreased hormone-sensitive lipase activity | "reduced ability to catalyze the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate" [GO:0033878] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0011698 | abnormal brown adipose tissue physiology | "any functional anomaly in the thermogenic form of adipose tissue that is composed of brown adipocytes" [MGI:smb] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
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MP:0014143 | decreased body fat mass | "decreased physical bulk or volume of fat in the whole body" [MGI:csmith] |
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Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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MP:0014146 | decreased white adipose tissue mass | "decreasd physical bulk or volume of white adipose tissue" [MGI:csmith] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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MP:0014169 | decreased brown adipose tissue mass | "decreased physical bulk or volume of brown adipose tissue" [MGI:csmith] |
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Allelic Composition: Lpin1fld/Lpin1fld Genetic Background: BALB/cByJ-Lpin1fld
Allelic Composition: Lpin1fld-2J/Lpin1fld-2J Genetic Background: C3H/HeJ-Lpin1fld-2J/J
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