ENSMUSG00000027610


Mus musculus

Features
Gene ID: ENSMUSG00000027610
  
Biological name :Gss
  
Synonyms : glutathione synthetase / Gss / P51855
  
Possible biological names infered from orthology : P48637
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H1
Gene start: 155563181
Gene end: 155592810
  
Corresponding Affymetrix probe sets: 10488879 (MoGene1.0st)   1441931_x_at (Mouse Genome 430 2.0 Array)   1448273_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135319
Ensembl peptide - ENSMUSP00000135392
Ensembl peptide - ENSMUSP00000078630
Ensembl peptide - ENSMUSP00000117266
Ensembl peptide - ENSMUSP00000122662
NCBI entrez gene - 14854     See in Manteia.
MGI - MGI:95852
RefSeq - NM_001291111
RefSeq - XM_006498781
RefSeq - NM_008180
RefSeq Peptide - NP_001278040
RefSeq Peptide - NP_032206
swissprot - A2AQN9
swissprot - H3BKH4
swissprot - P51855
swissprot - Q3UEE2
swissprot - Q541E2
swissprot - A2AQN7
Ensembl - ENSMUSG00000027610
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gssENSDARG00000037706Danio rerio
 GSSENSGALG00000003281Gallus gallus
 GSSENSG00000100983Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004887  Glutathione synthase, substrate-binding domain
 IPR005615  Glutathione synthase
 IPR014042  Glutathione synthase, alpha-helical
 IPR014049  Glutathione synthase, N-terminal, eukaryotic
 IPR014709  Glutathione synthase, C-terminal, eukaryotic
 IPR016185  Pre-ATP-grasp domain superfamily
 IPR037013  Glutathione synthase, substrate-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006520 cellular amino acid metabolic process IBA
 biological_processGO:0006750 glutathione biosynthetic process IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0009410 response to xenobiotic stimulus IEA
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0034612 response to tumor necrosis factor IEA
 biological_processGO:0043200 response to amino acid IEA
 biological_processGO:0046686 response to cadmium ion IDA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004363 glutathione synthase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016594 glycine binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043295 glutathione binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glutathione synthesis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Hoxa1tm8.2Mrc/Hoxa1tm8.2Mrc
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027610 Gss / P51855 / glutathione synthetase / P48637*  / complex






 

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