ENSMUSG00000027639


Mus musculus

Features
Gene ID: ENSMUSG00000027639
  
Biological name :Samhd1
  
Synonyms : SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 / Samhd1
  
Possible biological names infered from orthology : Q9Y3Z3
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H1
Gene start: 157097533
Gene end: 157135265
  
Corresponding Affymetrix probe sets: 10489107 (MoGene1.0st)   1418131_at (Mouse Genome 430 2.0 Array)   1420272_at (Mouse Genome 430 2.0 Array)   1420273_x_at (Mouse Genome 430 2.0 Array)   1434438_at (Mouse Genome 430 2.0 Array)   1444064_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000085880
Ensembl peptide - ENSMUSP00000124935
Ensembl peptide - ENSMUSP00000124599
Ensembl peptide - ENSMUSP00000105176
Ensembl peptide - ENSMUSP00000059717
NCBI entrez gene - 56045     See in Manteia.
MGI - MGI:1927468
RefSeq - NM_018851
RefSeq - NM_001139520
RefSeq Peptide - NP_061339
RefSeq Peptide - NP_001132992
swissprot - F6TVP2
swissprot - E0CXZ5
swissprot - E9PYG9
swissprot - E9Q0K6
swissprot - F8WJE0
Ensembl - ENSMUSG00000027639
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 samhd1ENSDARG00000071288Danio rerio
 SAMHD1ENSGALG00000001231Gallus gallus
 Q9Y3Z3ENSG00000101347Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR003607  HD/PDEase domain
 IPR006674  HD domain
 IPR013761  Sterile alpha motif/pointed domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Nucleobase catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002418 increased susceptibility to viral infection "greater likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gt(ROSA)26Sortm1(Actb-T,-GFP)Dalco/Gt(ROSA)26Sortm1(Actb-T,-GFP)Dalco
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Samhd1tm2.2Crs/Samhd1tm2.2Crs
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0005025 response to infection "the body s reaction to invasion and multiplication of microorganisms in its tissues, or the body s reaction to components of or toxins produced by pathogenic mircroorganisms " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Tbx1tm1Bld/Tbx1tm6(cre)Bld
Genetic Background: involves: 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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