ENSMUSG00000028339


Mus musculus

Features
Gene ID: ENSMUSG00000028339
  
Biological name :Col15a1
  
Synonyms : Col15a1 / Collagen alpha-1(XV) chain Restin / O35206
  
Possible biological names infered from orthology : collagen type XV alpha 1 chain / P39059
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: B1
Gene start: 47208161
Gene end: 47313167
  
Corresponding Affymetrix probe sets: 10504775 (MoGene1.0st)   1448755_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000080921
Ensembl peptide - ENSMUSP00000119292
Ensembl peptide - ENSMUSP00000118637
Ensembl peptide - ENSMUSP00000103359
Ensembl peptide - ENSMUSP00000103358
Ensembl peptide - ENSMUSP00000099981
NCBI entrez gene - 12819     See in Manteia.
MGI - MGI:88449
RefSeq - XM_006537601
RefSeq - NM_009928
RefSeq Peptide - NP_034058
swissprot - A2AJY2
swissprot - A2AJY6
swissprot - A2AJY4
swissprot - O35206
swissprot - A2AJY5
swissprot - A2AJY7
Ensembl - ENSMUSG00000028339
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 col15a1bENSDARG00000061848Danio rerio
 COL15A1ENSGALG00000034119Gallus gallus
 P39059ENSG00000204291Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P39061 / Col18a1 / Collagen alpha-1(XVIII) chain Endostatin Non-collagenous domain 1 / P39060* / collagen type XVIII alpha 1 chain*ENSMUSG0000000143536


Protein motifs (from Interpro)
Interpro ID Name
 IPR001791  Laminin G domain
 IPR008160  Collagen triple helix repeat
 IPR010515  Collagenase NC10/endostatin
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR016133  Insect cysteine-rich antifreeze protein
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005604 basement membrane IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000750 abnormal muscle regeneration "inability or defects in ability to repair muscle after injuries" [J:42574]
Show

Allelic Composition: Slc12a2tm2Bhk/Slc12a2tm2Bhk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0000751 myopathy "any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]
Show

Allelic Composition: Slc12a2tm2Bhk/Slc12a2tm2Bhk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0001544 abnormal cardiovascular system physiology "anomalous function of the blood, blood vessels, and/or the heart" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Slc12a2tm2Bhk/Slc12a2tm2Bhk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0002108 abnormal muscle morphology "abnormal development of muscle tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc12a2tm2Bhk/Slc12a2tm2Bhk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0003658 abnormal capillaries "malformation in the minute blood vessels that connect arterioles and venules" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96775]
Show

Allelic Composition: Slc12a2tm2Bhk/Slc12a2tm2Bhk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0004087 abnormal muscle fiber morphology "malformed or poorly developed muscle fibers, the cylindrical multinucleated muscle cells that contract when stimulated" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc12a2tm2Bhk/Slc12a2tm2Bhk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

 MP:0006055 abnormal vascular endothelial cell morphology "malformation in the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc12a2tm2Bhk/Slc12a2tm2Bhk
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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