ENSMUSG00000028348


Mus musculus

Features
Gene ID: ENSMUSG00000028348
  
Biological name :Cavin4
  
Synonyms : A2AMM0 / Caveolae-associated protein 4 / Cavin4
  
Possible biological names infered from orthology : Q5BKX8
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: B1
Gene start: 48663514
Gene end: 48673502
  
Corresponding Affymetrix probe sets: 10504902 (MoGene1.0st)   1420551_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030033
NCBI entrez gene - 68016     See in Manteia.
MGI - MGI:1915266
RefSeq - NM_026509
RefSeq Peptide - NP_080785
swissprot - A2AMM0
Ensembl - ENSMUSG00000028348
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cavin4aENSDARG00000038658Danio rerio
 cavin4bENSDARG00000056743Danio rerio
 CAVIN4ENSGALG00000026452Gallus gallus
 CAVIN4ENSG00000170681Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cavin1 / O54724 / Caveolae-associated protein 1 / Q6NZI2*ENSMUSG0000000404428
Cavin2 / Q63918 / Caveolae-associated protein 2 / O95810*ENSMUSG0000004595427
Cavin3 / Q91VJ2 / Caveolae-associated protein 3 / Q969G5*ENSMUSG0000003706016


Protein motifs (from Interpro)
Interpro ID Name
 IPR026752  Cavin family
 IPR033299  Caveolae-associated protein 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007266 Rho protein signal transduction ISO
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0055003 cardiac myofibril assembly ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005901 caveola ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030017 sarcomere IEA
 cellular_componentGO:0030018 Z disc ISO
 cellular_componentGO:0042383 sarcolemma IEA
 molecular_functionGO:0005096 GTPase activator activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004486 decreased response of heart to induced stress "decrease in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdh2tm1Glr/Cdh2tm1Glr,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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