ENSMUSG00000045954


Mus musculus

Features
Gene ID: ENSMUSG00000045954
  
Biological name :Cavin2
  
Synonyms : Caveolae-associated protein 2 / Cavin2 / Q63918
  
Possible biological names infered from orthology : O95810
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: C1.1
Gene start: 51289126
Gene end: 51302960
  
Corresponding Affymetrix probe sets: 10346164 (MoGene1.0st)   1416778_at (Mouse Genome 430 2.0 Array)   1416779_at (Mouse Genome 430 2.0 Array)   1443832_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055694
NCBI entrez gene - 20324     See in Manteia.
MGI - MGI:99513
RefSeq - NM_138741
RefSeq Peptide - NP_620080
swissprot - Q63918
Ensembl - ENSMUSG00000045954
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cavin2aENSDARG00000027611Danio rerio
 cavin2bENSDARG00000071196Danio rerio
 ENSGALG00000028174Gallus gallus
 CAVIN2ENSG00000168497Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cavin1 / O54724 / Caveolae-associated protein 1 / Q6NZI2*ENSMUSG0000000404434
Cavin3 / Q91VJ2 / Caveolae-associated protein 3 / Q969G5*ENSMUSG0000003706024
A2AMM0 / Cavin4 / Caveolae-associated protein 4 / Q5BKX8*ENSMUSG0000002834824


Protein motifs (from Interpro)
Interpro ID Name
 IPR026752  Cavin family
 IPR033298  Caveolae-associated protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0097320 plasma membrane tubulation IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005901 caveola IBA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005080 protein kinase C binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003180 abnormal pulmonary endothelial cell surface 
Show

Allelic Composition: Rorbtm1.1Df/Rorbtm1.1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Cavin3tm1(KOMP)Vlcg/Cavin3tm1(KOMP)Vlcg,Cavin2tm1(KOMP)Vlcg/Cavin2tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0003950 abnormal plasma membrane morphology "anomalous structure of the semipermeable membrane that encloses the cytoplasm of a cell" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rorbtm1.1Df/Rorbtm1.1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Cavin3tm1(KOMP)Vlcg/Cavin3tm1(KOMP)Vlcg,Cavin2tm1(KOMP)Vlcg/Cavin2tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0004007 abnormal lung vasculature "malformation or disorganization of the blood vessels of the lung" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rorbtm1.1Df/Rorbtm1.1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0006055 abnormal vascular endothelial cell morphology "malformation in the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rorbtm1.1Df/Rorbtm1.1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Cavin3tm1(KOMP)Vlcg/Cavin3tm1(KOMP)Vlcg,Cavin2tm1(KOMP)Vlcg/Cavin2tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0009115 abnormal fat cell morphology "any structural anomaly of a fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449]
Show

Allelic Composition: Rorbtm1.1Df/Rorbtm1.1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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