ENSMUSG00000037060


Mus musculus

Features
Gene ID: ENSMUSG00000037060
  
Biological name :Cavin3
  
Synonyms : Caveolae-associated protein 3 / Cavin3 / Q91VJ2
  
Possible biological names infered from orthology : Q969G5
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E3
Gene start: 105480083
Gene end: 105482300
  
Corresponding Affymetrix probe sets: 10566454 (MoGene1.0st)   1423771_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000044979
NCBI entrez gene - 109042     See in Manteia.
MGI - MGI:1923422
RefSeq - NM_028444
RefSeq Peptide - NP_082720
swissprot - Q91VJ2
Ensembl - ENSMUSG00000037060
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cavin2aENSDARG00000027611Danio rerio
 cavin2bENSDARG00000071196Danio rerio
 ENSGALG00000028174Gallus gallus
 CAVIN3ENSG00000170955Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cavin2 / Q63918 / Caveolae-associated protein 2 / O95810*ENSMUSG0000004595439
Cavin1 / O54724 / Caveolae-associated protein 1 / Q6NZI2*ENSMUSG0000000404430
A2AMM0 / Cavin4 / Caveolae-associated protein 4 / Q5BKX8*ENSMUSG0000002834822


Protein motifs (from Interpro)
Interpro ID Name
 IPR026752  Cavin family
 IPR033300  Caveolae-associated protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030866 cortical actin cytoskeleton organization IMP
 biological_processGO:0032922 circadian regulation of gene expression IMP
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:1901003 negative regulation of fermentation IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005901 caveola IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0005080 protein kinase C binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Il7tm1.1Mysl/Il7+
Genetic Background: B6.129P2(Cg)-Il7tm1.1Mysl

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Il7tm1.1Mysl/Il7+
Genetic Background: B6.129P2(Cg)-Il7tm1.1Mysl

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Il7tm1.1Mysl/Il7+
Genetic Background: B6.129P2(Cg)-Il7tm1.1Mysl

 MP:0003180 abnormal pulmonary endothelial cell surface 
Show

Allelic Composition: Cavin3tm1(KOMP)Vlcg/Cavin3tm1(KOMP)Vlcg,Cavin2tm1(KOMP)Vlcg/Cavin2tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0003950 abnormal plasma membrane morphology "anomalous structure of the semipermeable membrane that encloses the cytoplasm of a cell" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cavin3tm1(KOMP)Vlcg/Cavin3tm1(KOMP)Vlcg,Cavin2tm1(KOMP)Vlcg/Cavin2tm1(KOMP)Vlcg
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0005150 cachexia "general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Il7tm1.1Mysl/Il7+
Genetic Background: B6.129P2(Cg)-Il7tm1.1Mysl

 MP:0006055 abnormal vascular endothelial cell morphology "malformation in the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rorbtm1.1Df/Rorbtm1.1Df
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0010954 abnormal cellular respiration "anomaly in the enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)" [GO:0045333]
Show

Allelic Composition: Il7tm1.1Mysl/Il7+
Genetic Background: B6.129P2(Cg)-Il7tm1.1Mysl

 MP:0011174 lipodystrophy "abnormal or degenerative conditions of the body s adipose tissue resulting in bodily or focal loss and the appearance of redistribution of fat tissue; adipose tissue loss may be total, partial, or localized" [MGI:csmith]
Show

Allelic Composition: Il7tm1.1Mysl/Il7+
Genetic Background: B6.129P2(Cg)-Il7tm1.1Mysl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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