ENSMUSG00000028751


Mus musculus

Features
Gene ID: ENSMUSG00000028751
  
Biological name :Pla2g2e
  
Synonyms : Group IIE secretory phospholipase A2 / Pla2g2e / Q9QUL3
  
Possible biological names infered from orthology : phospholipase A2 group IIE / Q9NZK7
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D3
Gene start: 138877942
Gene end: 138882817
  
Corresponding Affymetrix probe sets: 10509590 (MoGene1.0st)   1420674_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030531
Ensembl peptide - ENSMUSP00000101429
Ensembl peptide - ENSMUSP00000101430
NCBI entrez gene - 26970     See in Manteia.
MGI - MGI:1349660
RefSeq - XM_006538949
RefSeq - NM_012044
RefSeq - XM_006538948
RefSeq Peptide - NP_036174
swissprot - Q3UG05
swissprot - Q9QUL3
swissprot - A2APQ4
Ensembl - ENSMUSG00000028751
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLA2G2EENSGALG00000014176Gallus gallus
 Q9NZK7ENSG00000188784Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pla2g2a / Mus musculus phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a), transcript variant 1, coding, mRNA. / P14555* / phospholipase A2 group IIA*ENSMUSG0000005890850
Q9QZT4 / Pla2g2f / Group IIF secretory phospholipase A2 / Q9BZM2* / phospholipase A2 group IIF*ENSMUSG0000002874942
Pla2g5 / phospholipase A2, group V / P39877*ENSMUSG0000004119341
Q9WVF6 / Pla2g2d / phospholipase A2, group IID / Q9UNK4*ENSMUSG0000004120239
Q9QXX3 / Pla2g10 / phospholipase A2, group X / O15496*ENSMUSG0000002268334
Q9Z0Y2 / Pla2g1b / Phospholipase A2 / P04054* / phospholipase A2 group IB*ENSMUSG0000002952232
Oc90 / Q9Z0L3 / Mus musculus otoconin 90 (Oc90), transcript variant 2, mRNA. / Q02509* / AC100868.1* / otoconin 90*ENSMUSG0000001500125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001211  Phospholipase A2
 IPR016090  Phospholipase A2 domain
 IPR033113  Phospholipase A2, histidine active site
 IPR036444  Phospholipase A2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0034374 low-density lipoprotein particle remodeling IMP
 biological_processGO:0050482 arachidonic acid secretion IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004623 phospholipase A2 activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
 molecular_functionGO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC
Acyl chain remodelling of PS
Acyl chain remodelling of PE
Acyl chain remodelling of PI
Acyl chain remodelling of PG
Synthesis of PA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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