ENSMUSG00000029004


Mus musculus

Features
Gene ID: ENSMUSG00000029004
  
Biological name :Kmt2e
  
Synonyms : Histone-lysine N-methyltransferase 2E / Kmt2e / Q3UG20
  
Possible biological names infered from orthology : lysine methyltransferase 2E / Q8IZD2
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: A3
Gene start: 23434441
Gene end: 23504235
  
Corresponding Affymetrix probe sets: 10520048 (MoGene1.0st)   1427236_a_at (Mouse Genome 430 2.0 Array)   1432601_at (Mouse Genome 430 2.0 Array)   1434704_at (Mouse Genome 430 2.0 Array)   1439107_a_at (Mouse Genome 430 2.0 Array)   1439108_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110781
Ensembl peptide - ENSMUSP00000143791
Ensembl peptide - ENSMUSP00000142568
Ensembl peptide - ENSMUSP00000142547
Ensembl peptide - ENSMUSP00000141393
Ensembl peptide - ENSMUSP00000141126
Ensembl peptide - ENSMUSP00000092569
NCBI entrez gene - 69188     See in Manteia.
MGI - MGI:1924825
RefSeq - XM_017321090
RefSeq - NM_026984
RefSeq - XM_006535805
RefSeq - XM_006535806
RefSeq - XM_006535807
RefSeq Peptide - NP_081260
swissprot - Q3UG20
swissprot - A0A0G2JH19
swissprot - A0A0A6YW47
swissprot - A0A087WSN9
swissprot - A0A0G2JDZ2
swissprot - A0A0G2JDX7
Ensembl - ENSMUSG00000029004
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kmt2eENSDARG00000007523Danio rerio
 KMT2EENSGALG00000008167Gallus gallus
 KMT2EENSG00000005483Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Setd5 / Q5XJV7 / Mus musculus SET domain containing 5 (Setd5), transcript variant 2, mRNA. / Q9C0A6* / SET domain containing 5*ENSMUSG0000003426926


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002446 neutrophil mediated immunity IMP
 biological_processGO:0006306 DNA methylation IMP
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0042119 neutrophil activation IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway ISS
 biological_processGO:0051568 histone H3-K4 methylation IEA
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle IEA
 biological_processGO:1905437 positive regulation of histone H3-K4 trimethylation IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0035327 transcriptionally active chromatin IEA
 molecular_functionGO:0003713 transcription coactivator activity ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0035064 methylated histone binding IEA
 molecular_functionGO:0042800 histone methyltransferase activity (H3-K4 specific) ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
PKMTs methylate histone lysines
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Pofut1cax/Pofut1cax
Genetic Background: involves: C57BL/6J * CAST/Ei

 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0000692 small spleen "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0000694 spleen hypoplasia "small size due to reduced cell number in the spleen" [J:43971]
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Allelic Composition: Erbb3tm2Cbm/Erbb3tm3Cbm,Erbb4tm1Fej/Erbb4tm1Fej,Cnptm1(cre)Kan/?
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0000706 small thymus "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0000715 decreased thymocyte number "fewer than expected number of precursors to T cells; these cells are lymphoid cells found in the thymus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Erbb3tm2Cbm/Erbb3tm3Cbm,Erbb4tm1Fej/Erbb4tm1Fej,Cnptm1(cre)Kan/?
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Erbb3tm2Cbm/Erbb3tm3Cbm,Erbb4tm1Fej/Erbb4tm1Fej,Cnptm1(cre)Kan/?
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Erbb3tm2Cbm/Erbb3tm3Cbm,Erbb4tm1Fej/Erbb4tm1Fej,Cnptm1(cre)Kan/?
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

 MP:0001658 increased mortality induced by gamma-irradiation "greater sensitivity to doses of ionizing radiation" [J:51834]
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Allelic Composition: Erbb3tm2Cbm/Erbb3tm3Cbm,Erbb4tm1Fej/Erbb4tm1Fej,Cnptm1(cre)Kan/?
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pofut1cax/Pofut1cax
Genetic Background: involves: C57BL/6J * CAST/Ei

 MP:0001823 thymus hypoplasia "small size due to reduced cell number in the thymus" [J:23255]
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Allelic Composition: Erbb3tm2Cbm/Erbb3tm3Cbm,Erbb4tm1Fej/Erbb4tm1Fej,Cnptm1(cre)Kan/?
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0002123 abnormal hematopoiesis "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pofut1cax/Pofut1cax
Genetic Background: involves: C57BL/6J * CAST/Ei

Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0002217 small lymph nodes "lymph nodes of decreased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0002398 abnormal bone marrow cell morphology/development "anomalous structure or formation of the cells found in the bone marrow" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0002401 abnormal lymphopoiesis "atypcial formation of lymphocytes and plasma cells from lymphoid stem cells which develop from the pluripotent hematopoietic stem cells in the bone marrow; these lymphoid stem cells differentiate into T-lymphocytes; B-lymphocytes; plasma cells; or NK-cells (natural killer cells), depending on the organ or tissues to which they migrate" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Erbb3tm2Cbm/Erbb3tm3Cbm,Erbb4tm1Fej/Erbb4tm1Fej,Cnptm1(cre)Kan/?
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0002414 abnormal myeloblast morphology/development "anomalous structure, formation, or numbers of the cells found in the bone marrow that give rise to the granulocyte line of blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0002415 abnormal neutrophil morphology/development "anomalous structure, differentiation, or number of the granular leukocytes that have a three- to five-lobed nucleus and a cytoplasm that contains inconspicuous granules stainable by neutral dyes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0002463 abnormal neutrophil physiology "abnormal function of these granular leukocytes, which stain with neutral dyes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0002594 low mean erythrocyte count "less than average numbers of red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0002686 globozoospermia "malformation of the acrosome resulting in a round sperm head" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0002874 decreased hemoglobin content "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0003179 decreased platelet count "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0003884 decreased macrophage count "fewer than the normal numbers of macrophages" [acv:Alicia Valenzuela, Genetic Resources Curator]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0004808 abnormal hematopoietic stem cell morphology "any structural anomaly of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pofut1cax/Pofut1cax
Genetic Background: involves: C57BL/6J * CAST/Ei

 MP:0004809 increased hematopoietic stem cell number "greater cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pofut1cax/Pofut1cax
Genetic Background: involves: C57BL/6J * CAST/Ei

 MP:0004810 decreased hematopoietic stem cell number "reduced cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

Allelic Composition: Kmt2etm1Nik/Kmt2etm1Nik
Genetic Background: B6.Cg-Kmtetm1Nik

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0005018 decreased T cell number "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0005089 decreased double-negative T cell count "reduced numbers of the subset of T cells found in the thymus that express neither CD4 nor CD8 " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0005092 decreased double-positive T cell count "less than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0005251 blepharitis "inflammation of the eyelids" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0008040 decreased NK T cell number "reduced number of the distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments" [GO:0001865]
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Allelic Composition: Kmt2etm1Nik/Kmt2etm1Nik
Genetic Background: B6.Cg-Kmtetm1Nik

 MP:0008045 decreased NK cell number "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
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Allelic Composition: Kmt2etm1Nik/Kmt2etm1Nik
Genetic Background: B6.Cg-Kmtetm1Nik

 MP:0008111 abnormal granulocyte differentiaton "atypical production of or inability to produce leukocytes that have abundant granules in the cytoplasm, including basophils, neutrophils, and eosinophils" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0008208 decreased pro-B cell number "reduced number of the progenitor cells of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but are not yet fully committed to the B cell lineage until the expression of PAX5 occurs" [CL:0000826, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0008209 decreased pre-B cell number "reduced number of the cells in the B lymphocyte lineage that have undergone VDJ rearrangement of the immunoglobulin heavy chain and are in the process of V-J rearrangement of the light chain: these cells express mu heavy chain on the cell surface" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0008813 decreased common myeloid progenitor cell number "reduced number of progenitor cells committed to myeloid lineage, including the megakaryocyte and erythroid lineages" [CL:0000049, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0008850 increased hemoglobin concentration distribution width "higher than normal standard deviation of the distribution of erythrocytes by their cellular (individual) hemoglobin concentrations; high HDW is indicative of some types of anemia/thalassemia" [MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Kmt2etm1Nik/Kmt2etm1Nik
Genetic Background: B6.Cg-Kmtetm1Nik

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Kmt2etm1.1Hjf/Kmt2etm1.1Hjf
Genetic Background: B6.129P2-Kmtetm1.1Hjf

Allelic Composition: Kmt2etm1Nik/Kmt2etm1Nik
Genetic Background: B6.Cg-Kmtetm1Nik

 MP:0011112 partial lethality during fetal growth through weaning "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and weaning age (Mus: E14 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

 MP:0013320 dilated seminal vesicles "an expansion in the lumen volume of either of the paired sac-like glandular structures situated posterolateral to the urinary bladder in the male and functioning as part of the reproductive system, as by stretching or distention" [MGI:Anna]
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Allelic Composition: Kmt2etm1Apa/Kmt2etm1Apa
Genetic Background: 129S6/SvEvTac-Kmt2etm1Apa

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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