ENSMUSG00000029096


Mus musculus

Features
Gene ID: ENSMUSG00000029096
  
Biological name :Htra3
  
Synonyms : Htra3 / Q9D236 / Serine protease HTRA3
  
Possible biological names infered from orthology : HtrA serine peptidase 3 / P83110
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: B3
Gene start: 35652023
Gene end: 35679782
  
Corresponding Affymetrix probe sets: 10529485 (MoGene1.0st)   1419292_at (Mouse Genome 430 2.0 Array)   1427029_at (Mouse Genome 430 2.0 Array)   1431762_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109871
Ensembl peptide - ENSMUSP00000144597
Ensembl peptide - ENSMUSP00000144550
Ensembl peptide - ENSMUSP00000144051
Ensembl peptide - ENSMUSP00000084910
NCBI entrez gene - 78558     See in Manteia.
MGI - MGI:1925808
RefSeq - XM_011240796
RefSeq - NM_001042615
RefSeq - NM_030127
RefSeq - XM_006504186
RefSeq Peptide - NP_001036080
RefSeq Peptide - NP_084403
swissprot - A0A0J9YVC4
swissprot - A0A0J9YU80
swissprot - A0A0J9YV92
swissprot - Q9D236
Ensembl - ENSMUSG00000029096
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HTRA3ENSDARG00000010925Danio rerio
 htra3aENSDARG00000052895Danio rerio
 HTRA3ENSGALG00000034673Gallus gallus
 HTRA3ENSG00000170801Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Htra1 / Q9R118 / Serine protease HTRA1 / Q92743* / HtrA serine peptidase 1*ENSMUSG0000000620556
Htra4 / A2RT60 / Serine protease HTRA4 / P83105* / HtrA serine peptidase 4*ENSMUSG0000003740652
Htra2 / Q9JIY5 / Serine protease HTRA2, mitochondrial / O43464* / HtrA serine peptidase 2*ENSMUSG0000006832940


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR001478  PDZ domain
 IPR001940  Peptidase S1C
 IPR002350  Kazal domain
 IPR009003  Peptidase S1, PA clan
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR036034  PDZ superfamily
 IPR036058  Kazal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IDA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004175 endopeptidase activity ISO
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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