ENSMUSG00000029131


Mus musculus

Features
Gene ID: ENSMUSG00000029131
  
Biological name :Dnajb6
  
Synonyms : Dnajb6 / DnaJ homolog subfamily B member 6 / O54946
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: B1
Gene start: 29735688
Gene end: 29818134
  
Corresponding Affymetrix probe sets: 10354404 (MoGene1.0st)   10395976 (MoGene1.0st)   10481868 (MoGene1.0st)   10520445 (MoGene1.0st)   10585533 (MoGene1.0st)   1429776_a_at (Mouse Genome 430 2.0 Array)   1429777_at (Mouse Genome 430 2.0 Array)   1434035_at (Mouse Genome 430 2.0 Array)   1448234_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142783
Ensembl peptide - ENSMUSP00000117159
Ensembl peptide - ENSMUSP00000142878
Ensembl peptide - ENSMUSP00000143639
Ensembl peptide - ENSMUSP00000008733
Ensembl peptide - ENSMUSP00000012734
Ensembl peptide - ENSMUSP00000110488
NCBI entrez gene - 23950     See in Manteia.
MGI - MGI:1344381
RefSeq - XM_006535708
RefSeq - NM_001037940
RefSeq - NM_001037941
RefSeq - NM_001127367
RefSeq - NM_011847
RefSeq - XM_006535707
RefSeq Peptide - NP_035977
RefSeq Peptide - NP_001033029
RefSeq Peptide - NP_001033030
RefSeq Peptide - NP_001120839
swissprot - A0A0G2JER9
swissprot - A0A0G2JGN9
swissprot - F6YRQ2
swissprot - O54946
swissprot - A0A0G2JEI3
swissprot - G3X8S5
Ensembl - ENSMUSG00000029131
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNAJB6ENSGALG00000006477Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dnajb7 / Q9QYI8 / DnaJ homolog subfamily B member 7 / Q7Z6W7* / DnaJ heat shock protein family (Hsp40) member B7*ENSMUSG0000004710847
Dnajb3ENSMUSG0000008198444
Dnajb2 / Q9QYI5 / DnaJ homolog subfamily B member 2 / P25686* / DnaJ heat shock protein family (Hsp40) member B2*ENSMUSG0000002620342
Dnajb8 / Q9QYI7 / DnaJ homolog subfamily B member 8 / Q8NHS0* / DnaJ heat shock protein family (Hsp40) member B8*ENSMUSG0000004820637
Dnajb5 / O89114 / Mus musculus DnaJ heat shock protein family (Hsp40) member B5 (Dnajb5), transcript variant 3, mRNA. / O75953* / DnaJ heat shock protein family (Hsp40) member B5*ENSMUSG0000003605226
Dnajb4 / Q9D832 / DnaJ homolog subfamily B member 4 / Q9UDY4* / DnaJ heat shock protein family (Hsp40) member B4*ENSMUSG0000002803526
4930503B20Rik / RIKEN cDNA 4930503B20 geneENSMUSG0000009020224
Dnajb1 / Q9QYJ3 / DnaJ homolog subfamily B member 1 / P25685* / DnaJ heat shock protein family (Hsp40) member B1*ENSMUSG0000000548324
Q80Y75 / Dnajb13 / DnaJ homolog subfamily B member 13 / P59910* / DnaJ heat shock protein family (Hsp40) member B13*ENSMUSG0000003070824
Dnajb9 / Q9QYI6 / DnaJ homolog subfamily B member 9 / Q9UBS3* / DnaJ heat shock protein family (Hsp40) member B9*ENSMUSG0000001490516


Protein motifs (from Interpro)
Interpro ID Name
 IPR001623  DnaJ domain
 IPR018253  DnaJ domain, conserved site
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding ISO
 biological_processGO:0030036 actin cytoskeleton organization IMP
 biological_processGO:0030198 extracellular matrix organization IMP
 biological_processGO:0032781 positive regulation of ATPase activity IEA
 biological_processGO:0032880 regulation of protein localization ISO
 biological_processGO:0034504 protein localization to nucleus IMP
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0045109 intermediate filament organization ISO
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0060710 chorio-allantoic fusion IMP
 biological_processGO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development IMP
 biological_processGO:0060717 chorion development IMP
 biological_processGO:0061077 chaperone-mediated protein folding ISO
 biological_processGO:0090084 negative regulation of inclusion body assembly ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0001671 ATPase activator activity ISO
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031072 heat shock protein binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0044183 protein binding involved in protein folding ISO
 molecular_functionGO:0051082 unfolded protein binding ISO
 molecular_functionGO:0051087 chaperone binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Hes1tm1Fgu/Hes1tm1Fgu,Hes5tm1Fgu/Hes5tm1Fgu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Hes1tm1Fgu/Hes1tm1Fgu,Hes5tm1Fgu/Hes5tm1Fgu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0002086 abnormal extraembryonic tissue morphology "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Hes1tm1Fgu/Hes1tm1Fgu,Hes5tm1Fgu/Hes5tm1Fgu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0003403 absent placental labyrinth "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:73417]
Show

Allelic Composition: Hes1tm1Fgu/Hes1tm1Fgu,Hes5tm1Fgu/Hes5tm1Fgu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0009657 failure of chorioallantoic fusion "failure to initiate and/or complete the formation of a highly vascularized extra-embryonic fetal membrane by fusion of the chorion and allantois" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hes1tm1Fgu/Hes1tm1Fgu,Hes5tm1Fgu/Hes5tm1Fgu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Hes1tm1Fgu/Hes1tm1Fgu,Hes5tm1Fgu/Hes5tm1Fgu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr