ENSMUSG00000029375


Mus musculus

Features
Gene ID: ENSMUSG00000029375
  
Biological name :Cxcl15
  
Synonyms : Cxcl15 / C-X-C motif chemokine 15 / Q9WVL7
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: E1
Gene start: 90794534
Gene end: 90803067
  
Corresponding Affymetrix probe sets: 10523145 (MoGene1.0st)   1421404_at (Mouse Genome 430 2.0 Array)   1456428_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031322
NCBI entrez gene - 20309     See in Manteia.
MGI - MGI:1339941
RefSeq - NM_011339
RefSeq Peptide - NP_035469
swissprot - Q9WVL7
Ensembl - ENSMUSG00000029375
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cxcl19ENSDARG00000102776Danio rerio
 ENSGALG00000046160Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cxcl5 / P50228 / C-X-C motif chemokine 5 GCP-2(1-78) GCP-2(9-78) / CXCL6* / P80162* / P42830* / C-X-C motif chemokine ligand 6* / C-X-C motif chemokine ligand 5*ENSMUSG0000002937120
Cxcl1 / P12850 / Growth-regulated alpha protein KC(5-72) / CXCL3* / CXCL2* / P19876* / P09341* / P19875* / C-X-C motif chemokine ligand 2* / C-X-C motif chemokine ligand 1* / C-X-C motif ch...ENSMUSG0000002938019
Ppbp / pro-platelet basic protein / P02775*ENSMUSG0000002937219
Cxcl2 / P10889 / C-X-C motif chemokine 2 / CXCL3* / CXCL1* / P19876* / P09341* / P19875* / C-X-C motif chemokine ligand 2* / C-X-C motif chemokine ligand 3* / C-X-C motif chemokine ligand 1*ENSMUSG0000005842717
Cxcl3 / Q6W5C0 / C-X-C motif chemokine 3 / CXCL1* / CXCL2* / P09341* / P19875* / P19876* / C-X-C motif chemokine ligand 3* / C-X-C motif chemokine ligand 2* / C-X-C motif chemokine ligand 1*ENSMUSG0000002937914


Protein motifs (from Interpro)
Interpro ID Name
 IPR001089  CXC chemokine
 IPR001811  Chemokine interleukin-8-like domain
 IPR018048  CXC chemokine, conserved site
 IPR033899  CXC Chemokine domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002690 positive regulation of leukocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis IDA
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010818 T cell chemotaxis IBA
 biological_processGO:0030097 hemopoiesis IDA
 biological_processGO:0030593 neutrophil chemotaxis IDA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IDA
 molecular_functionGO:0048248 CXCR3 chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptch1tm1Zim/Ptch1+
Genetic Background: involves: 129/Sv * CD-1

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ptch1tm1Zim/Ptch1+
Genetic Background: involves: 129/Sv * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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