ENSMUSG00000029410


Mus musculus

Features
Gene ID: ENSMUSG00000029410
  
Biological name :Ppef2
  
Synonyms : O35385 / Ppef2 / Serine/threonine-protein phosphatase with EF-hands 2
  
Possible biological names infered from orthology : O14830 / protein phosphatase with EF-hand domain 2
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E2
Gene start: 92226679
Gene end: 92256278
  
Corresponding Affymetrix probe sets: 10531348 (MoGene1.0st)   1422159_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031359
Ensembl peptide - ENSMUSP00000144157
NCBI entrez gene - 19023     See in Manteia.
MGI - MGI:1342304
RefSeq - XM_006534817
RefSeq - NM_011148
RefSeq Peptide - NP_035278
swissprot - O35385
Ensembl - ENSMUSG00000029410
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU695117.1ENSDARG00000104980Danio rerio
 PPEF2ENSGALG00000011524Gallus gallus
 PPEF2ENSG00000156194Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ppef1 / O35655 / Serine/threonine-protein phosphatase with EF-hands 1 / O14829* / protein phosphatase with EF-hand domain 1*ENSMUSG0000006216840
Ppp5c / Q60676 / Serine/threonine-protein phosphatase 5 / P53041* / protein phosphatase 5 catalytic subunit*ENSMUSG0000000309918


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR002048  EF-hand domain
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR011992  EF-hand domain pair
 IPR012008  Serine/threonine-protein phosphatase with EF-hands
 IPR013235  PPP domain
 IPR018247  EF-Hand 1, calcium-binding site
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0010801 negative regulation of peptidyl-threonine phosphorylation ISO
 biological_processGO:0043409 negative regulation of MAPK cascade ISO
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050906 detection of stimulus involved in sensory perception IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity ISS
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0030544 Hsp70 protein binding ISO
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051879 Hsp90 protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ppef1tm1Nat/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Ppef1tm1Nat/Ppef1tm1Nat,Ppef2tm1Nat/Ppef2tm1Nat
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Ppef1tm1Nat/Y,Ppef2tm1Nat/Ppef2tm1Nat
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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