ENSMUSG00000062168


Mus musculus

Features
Gene ID: ENSMUSG00000062168
  
Biological name :Ppef1
  
Synonyms : O35655 / Ppef1 / Serine/threonine-protein phosphatase with EF-hands 1
  
Possible biological names infered from orthology : O14829 / protein phosphatase with EF-hand domain 1
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F4
Gene start: 160623094
Gene end: 160735765
  
Corresponding Affymetrix probe sets: 10607602 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000071191
Ensembl peptide - ENSMUSP00000121692
Ensembl peptide - ENSMUSP00000123408
NCBI entrez gene - 237178     See in Manteia.
MGI - MGI:1097157
RefSeq - XM_017318481
RefSeq - NM_011147
RefSeq - XM_011247818
RefSeq - XM_017318480
RefSeq Peptide - NP_035277
swissprot - Q3UQZ5
swissprot - B7ZCG2
swissprot - O35655
Ensembl - ENSMUSG00000062168
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppef1ENSDARG00000020191Danio rerio
 PPEF1ENSGALG00000016522Gallus gallus
 PPEF1ENSG00000086717Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ppef2 / O35385 / Serine/threonine-protein phosphatase with EF-hands 2 / O14830* / protein phosphatase with EF-hand domain 2*ENSMUSG0000002941046
Ppp5c / Q60676 / Serine/threonine-protein phosphatase 5 / P53041* / protein phosphatase 5 catalytic subunit*ENSMUSG0000000309921


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR002048  EF-hand domain
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR011992  EF-hand domain pair
 IPR012008  Serine/threonine-protein phosphatase with EF-hands
 IPR013235  PPP domain
 IPR018247  EF-Hand 1, calcium-binding site
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0050906 detection of stimulus involved in sensory perception IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity ISS
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Calcrtm1Dgal/Calcr+,Iapptm1Sgm/Iapp+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Ppef1tm1Nat/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Ppef1tm1Nat/Ppef1tm1Nat,Ppef2tm1Nat/Ppef2tm1Nat
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Ppef1tm1Nat/Y,Ppef2tm1Nat/Ppef2tm1Nat
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030324 Rho / P15409 / Rhodopsin / P08100*  / reaction






 

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