ENSG00000086717


Homo sapiens

Features
Gene ID: ENSG00000086717
  
Biological name :PPEF1
  
Synonyms : O14829 / PPEF1 / protein phosphatase with EF-hand domain 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p22.13
Gene start: 18675909
Gene end: 18827921
  
Corresponding Affymetrix probe sets: 206547_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419948
Ensembl peptide - ENSP00000354871
Ensembl peptide - ENSP00000418623
Ensembl peptide - ENSP00000419273
Ensembl peptide - ENSP00000341892
NCBI entrez gene - 5475     See in Manteia.
OMIM - 300109
RefSeq - XM_017029612
RefSeq - NM_006240
RefSeq - NM_152224
RefSeq - NM_152226
RefSeq - XM_005274553
RefSeq Peptide - NP_689410
RefSeq Peptide - NP_006231
RefSeq Peptide - NP_689412
swissprot - F8WC69
swissprot - H7C592
swissprot - C9JY08
swissprot - A0A024RBZ9
swissprot - O14829
Ensembl - ENSG00000086717
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppef1ENSDARG00000020191Danio rerio
 PPEF1ENSGALG00000016522Gallus gallus
 Ppef1ENSMUSG00000062168Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPEF2 / O14830 / protein phosphatase with EF-hand domain 2ENSG0000015619448
PPP5C / P53041 / protein phosphatase 5 catalytic subunitENSG0000001148520


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR002048  EF-hand domain
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR011992  EF-hand domain pair
 IPR012008  Serine/threonine-protein phosphatase with EF-hands
 IPR013235  PPP domain
 IPR018247  EF-Hand 1, calcium-binding site
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation TAS
 biological_processGO:0022400 regulation of rhodopsin mediated signaling pathway TAS
 biological_processGO:0050906 detection of stimulus involved in sensory perception IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity TAS
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163914 RHO / P08100 / rhodopsin  / reaction






 

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