ENSG00000156194


Homo sapiens

Features
Gene ID: ENSG00000156194
  
Biological name :PPEF2
  
Synonyms : O14830 / PPEF2 / protein phosphatase with EF-hand domain 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q21.1
Gene start: 75859864
Gene end: 75902571
  
Corresponding Affymetrix probe sets: 208411_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000286719
Ensembl peptide - ENSP00000483398
Ensembl peptide - ENSP00000426186
NCBI entrez gene - 5470     See in Manteia.
OMIM - 602256
RefSeq - NM_006239
RefSeq - XM_011532039
RefSeq Peptide - NP_006230
swissprot - E7EPQ9
swissprot - O14830
Ensembl - ENSG00000156194
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU695117.1ENSDARG00000104980Danio rerio
 PPEF2ENSGALG00000011524Gallus gallus
 Ppef2ENSMUSG00000029410Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPEF1 / O14829 / protein phosphatase with EF-hand domain 1ENSG0000008671741
PPP5C / P53041 / protein phosphatase 5 catalytic subunitENSG0000001148519


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR011992  EF-hand domain pair
 IPR012008  Serine/threonine-protein phosphatase with EF-hands
 IPR013235  PPP domain
 IPR018247  EF-Hand 1, calcium-binding site
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation TAS
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0010801 negative regulation of peptidyl-threonine phosphorylation IDA
 biological_processGO:0043405 regulation of MAP kinase activity IC
 biological_processGO:0043409 negative regulation of MAPK cascade IDA
 biological_processGO:0043506 regulation of JUN kinase activity IC
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050906 detection of stimulus involved in sensory perception IEA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0001917 photoreceptor inner segment IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity TAS
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0030544 Hsp70 protein binding IDA
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051879 Hsp90 protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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