ENSMUSG00000029599


Mus musculus

Features
Gene ID: ENSMUSG00000029599
  
Biological name :Ddx54
  
Synonyms : ATP-dependent RNA helicase DDX54 / Ddx54 / Q8K4L0
  
Possible biological names infered from orthology : DEAD-box helicase 54 / Q8TDD1
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 120612739
Gene end: 120628592
  
Corresponding Affymetrix probe sets: 10525111 (MoGene1.0st)   1438853_x_at (Mouse Genome 430 2.0 Array)   1447882_x_at (Mouse Genome 430 2.0 Array)   1460396_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031598
NCBI entrez gene - 71990     See in Manteia.
MGI - MGI:1919240
RefSeq - NM_028041
RefSeq Peptide - NP_082317
swissprot - Q8K4L0
Ensembl - ENSMUSG00000029599
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx54ENSDARG00000105286Danio rerio
 DDX54ENSGALG00000007490Gallus gallus
 DDX54ENSG00000123064Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR012541  DBP10, C-terminal
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR033517  DDX54/DBP10 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0016070 RNA metabolic process IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity ISO
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030331 estrogen receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
Show

Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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