ENSMUSG00000030423


Mus musculus

Features
Gene ID: ENSMUSG00000030423
  
Biological name :Pop4
  
Synonyms : Pop4 / processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae) / Q9CR08
  
Possible biological names infered from orthology : O95707 / POP4 homolog, ribonuclease P/MRP subunit
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 38261996
Gene end: 38271423
  
Corresponding Affymetrix probe sets: 10562578 (MoGene1.0st)   1448419_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145810
Ensembl peptide - ENSMUSP00000146204
Ensembl peptide - ENSMUSP00000146119
Ensembl peptide - ENSMUSP00000032585
NCBI entrez gene - 66161     See in Manteia.
MGI - MGI:1913411
RefSeq - NM_025390
RefSeq - XM_006540287
RefSeq Peptide - NP_079666
swissprot - A0A0U1RQ13
swissprot - Q9CR08
swissprot - A0A0U1RP33
Ensembl - ENSMUSG00000030423
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pop4ENSDARG00000101472Danio rerio
 POP4ENSGALG00000041972Gallus gallus
 POP4ENSG00000105171Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002730  Ribonuclease P/MRP, subunit p29
 IPR016848  Ribonuclease P/MRP, p29 subunit
 IPR023534  Rof/RNase P-like
 IPR036980  Ribonuclease P/MRP, subunit p29 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001682 tRNA 5"-leader removal IEA
 biological_processGO:0006364 rRNA processing IBA
 biological_processGO:0006379 mRNA cleavage IEA
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 cellular_componentGO:0000172 ribonuclease MRP complex IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005655 nucleolar ribonuclease P complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0030677 ribonuclease P complex IBA
 cellular_componentGO:0030681 multimeric ribonuclease P complex IEA
 molecular_functionGO:0000171 ribonuclease MRP activity IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004526 ribonuclease P activity IEA
 molecular_functionGO:0004540 ribonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0033204 ribonuclease P RNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mc4rMhdahwe13/Mc4r+
Genetic Background: C3HeB/FeJ-Mc4rMhdahwe13

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pfn1tm1a(EUCOMM)Wtsi/Pfn1+
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd Pfn1tm1a(EUCOMM)Wtsi/Wtsi

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Mc4rMhdahwe13/Mc4r+
Genetic Background: C3HeB/FeJ-Mc4rMhdahwe13

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Pitx3tm1.1(KOMP)Vlcg/Pitx3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Pitx3tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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