ENSMUSG00000030609


Mus musculus

Features
Gene ID: ENSMUSG00000030609
  
Biological name :Aen
  
Synonyms : Aen / Apoptosis-enhancing nuclease / Q9CZI9
  
Possible biological names infered from orthology : Q8WTP8
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: D2
Gene start: 78895854
Gene end: 78911209
  
Corresponding Affymetrix probe sets: 10554233 (MoGene1.0st)   1423957_at (Mouse Genome 430 2.0 Array)   1437373_at (Mouse Genome 430 2.0 Array)   1445040_at (Mouse Genome 430 2.0 Array)   1450506_a_at (Mouse Genome 430 2.0 Array)   1451186_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103048
Ensembl peptide - ENSMUSP00000146246
Ensembl peptide - ENSMUSP00000145715
Ensembl peptide - ENSMUSP00000117331
Ensembl peptide - ENSMUSP00000103044
Ensembl peptide - ENSMUSP00000103046
NCBI entrez gene - 68048     See in Manteia.
MGI - MGI:1915298
RefSeq - XM_006541137
RefSeq - NM_001162939
RefSeq - NM_026531
RefSeq Peptide - NP_001156411
RefSeq Peptide - NP_080807
swissprot - Q9CZI9
swissprot - D3Z516
swissprot - A0A0U1RNV2
swissprot - A0A0U1RQ47
Ensembl - ENSMUSG00000030609
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 isg20ENSDARG00000079783Danio rerio
 AENENSGALG00000044204Gallus gallus
 AENENSG00000181026Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Isg20l2 / interferon stimulated exonuclease gene 20 like 2 / Q9H9L3*ENSMUSG0000004803936
Rexo4 / Q6PAQ4 / RNA exonuclease 4 / Q9GZR2* / REX4 homolog, 3-5 exonuclease*ENSMUSG0000005240626
Isg20 / Q9JL16 / Interferon-stimulated 20 kDa protein / Q96AZ6* / interferon stimulated exonuclease gene 20*ENSMUSG0000003923625


Protein motifs (from Interpro)
Interpro ID Name
 IPR012337  Ribonuclease H-like superfamily
 IPR013520  Exonuclease, RNase T/DNA polymerase III
 IPR036397  Ribonuclease H superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010212 response to ionizing radiation ISO
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISS
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISS
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0031965 nuclear membrane ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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