ENSMUSG00000030827


Mus musculus

Features
Gene ID: ENSMUSG00000030827
  
Biological name :Fgf21
  
Synonyms : Fgf21 / Fibroblast growth factor 21 / Q9JJN1
  
Possible biological names infered from orthology : Q9NSA1
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 45613886
Gene end: 45615490
  
Corresponding Affymetrix probe sets: 10563344 (MoGene1.0st)   1422916_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033099
NCBI entrez gene - 56636     See in Manteia.
MGI - MGI:1861377
RefSeq - XM_011250880
RefSeq - NM_020013
RefSeq - XM_011250879
RefSeq Peptide - NP_064397
swissprot - Q9JJN1
Ensembl - ENSMUSG00000030827
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FGF21ENSG00000105550Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fgf23 / Q9EPC2 / Fibroblast growth factor 23 / Q9GZV9*ENSMUSG0000000018230
Fgf15 / O35622 / Fibroblast growth factor 15 / FGF19* / O95750* / fibroblast growth factor 19*ENSMUSG0000003107329


Protein motifs (from Interpro)
Interpro ID Name
 IPR002209  Fibroblast growth factor family
 IPR008996  Cytokine IL1/FGF
 IPR028292  Fibroblast growth factor 21
 IPR035444  Fibroblast growth factor 15/19/21


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IGI
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010898 positive regulation of triglyceride catabolic process IEA
 biological_processGO:0014823 response to activity IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071377 cellular response to glucagon stimulus IEA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus IEA
 biological_processGO:0072577 endothelial cell apoptotic process IEA
 biological_processGO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway IGI
 biological_processGO:1901215 negative regulation of neuron death IEA
 biological_processGO:1904640 response to methionine IEA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Cellular hexose transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000003 abnormal adipose tissue morphology "structural anomaly of the connective tissue composed of fat cells enmeshed in areolar tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0000005 increased brown fat amount "increased amount of thermogenic tissue in the body that is composed of cells containing multiple small fat droplets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:14208]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0000008 increased white fat amount "increased quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0000189 hypoglycemia "low levels of plasma glucose in the circulating blood; this generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Itga4tm1Mgin/Itga4tm1Mgin
Genetic Background: Not Specified

 MP:0000609 abnormal liver physiology "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0001257 increased body length "increased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cspg4tm1Ychan/Cspg4tm1Ychan,Olig2tm2(TVA,cre)Rth/Olig2+
Genetic Background: involves: 129 * C57BL/6N

 MP:0001259 abnormal body weight "anomaly in average weight compared to the norm" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0001547 abnormal lipid level "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0001553 abnormal circulating free fatty acids level "anomalous blood concentrations of organic, monobasic acids derived from hydrocarbons and which are complexed with serum albumin for transport; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0001554 increased circulating free fatty acid level "higher than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146]
Show

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0001752 abnormal hypothalamus secretion "altered ability of the hypothalamus to release its contents" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0001783 decreased white fat amount "reduced quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0002118 abnormal lipid homeostasis "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ano6Gt(RRF355)Byg/Ano6Gt(RRF355)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002575 increased circulating ketone body level "greater than the normal amount of acetoacetate, 3-hydroxybutyrate and acteone in the blood; produced by fatty acid and carbohydrate metabolism and seen in conditions such as starvation and diabetes mellitus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator, J:71968]
Show

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0002702 decreased circulating free fatty acid level "lower than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0002981 increased liver weight "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0003383 abnormal gluconeogenesis "anomaly in the formation of glucose from noncarbohydrates, such as proteins or fat" [J:93896]
Show

Allelic Composition: Itga4tm1Mgin/Itga4tm1Mgin
Genetic Background: Not Specified

 MP:0003408 increased width of hypertrophic chondrocyte zone "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Cspg4tm1Ychan/Cspg4tm1Ychan,Olig2tm2(TVA,cre)Rth/Olig2+
Genetic Background: involves: 129 * C57BL/6N

 MP:0003458 decreased circulating ketone body level "less than the normal amount of acetoacetate, 3-hydroxybutyrate and acteone in the blood; produced by fatty acid and carbohydrate metabolism and seen in conditions such as starvation and diabetes mellitus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Itga4tm1Mgin/Itga4tm1Mgin
Genetic Background: Not Specified

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0004357 long tibia "increased length of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Cspg4tm1Ychan/Cspg4tm1Ychan,Olig2tm2(TVA,cre)Rth/Olig2+
Genetic Background: involves: 129 * C57BL/6N

 MP:0004701 decreased circulating insulin-like growth factor I level "reduced blood concentration of this polypeptide hormone with growth-regulating, insulin-like, and mitogenic activities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cspg4tm1Ychan/Cspg4tm1Ychan,Olig2tm2(TVA,cre)Rth/Olig2+
Genetic Background: involves: 129 * C57BL/6N

 MP:0005120 decreased circulating growth hormone level "less than the expected blood concentration of the hormone that promotes body growth, fat mobilization, and inhibition of glucose utilization" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cspg4tm1Ychan/Cspg4tm1Ychan,Olig2tm2(TVA,cre)Rth/Olig2+
Genetic Background: involves: 129 * C57BL/6N

 MP:0005123 increased circulating growth hormone level "greater than the expected blood concentration of the hormone that promotes body growth, fat mobilization, and inhibition of glucose utilization" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cspg4tm1Ychan/Cspg4tm1Ychan,Olig2tm2(TVA,cre)Rth/Olig2+
Genetic Background: involves: 129 * C57BL/6N

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0005282 decreased fatty acid level "less than normal non-circulating level of organic, monobasic acids derived from hydrocarbons; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0005290 decreased oxygen consumption "less than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Itga4tm1Mgin/Itga4tm1Mgin
Genetic Background: Not Specified

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Foxg1tm1M/Foxg1tm1M
Genetic Background: involves: 129S1/Sv

 MP:0005449 abnormal food intake "anomalous total number of calories taken in daily when compared to the norm" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0005534 decreased body temperature "less than the level of heat natural to a living being" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Itga4tm1Mgin/Itga4tm1Mgin
Genetic Background: Not Specified

 MP:0005669 increased circulating leptin level "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0005670 abnormal white fat physiology "functional aberration in the connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Apctm1Tno/Apctm1Tno,Lgr5tm1(cre/ERT2)Cle/Lgr5+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

 MP:0006398 increased long bone epiphyseal plate size "greater than the normal size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Cspg4tm1Ychan/Cspg4tm1Ychan,Olig2tm2(TVA,cre)Rth/Olig2+
Genetic Background: involves: 129 * C57BL/6N

 MP:0008033 impaired lipolysis "reduction in the rate of the hydrolysis of fat into free fatty acids " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0008034 enhanced lipolysis "increase in the rate of the hydrolysis of fat into free fatty acids " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0008874 decreased sensitivity to xenobiotics "increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Itga4tm1Mgin/Itga4tm1Mgin
Genetic Background: Not Specified

Allelic Composition: Fgf21tm1Lex/Fgf21tm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6N

 MP:0009116 abnormal brown fat cell morphology "any structural anomaly of cells from the thermogenic form of adipose tissue found in newborns of many species, including humans, and in hibernating mammals; brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation; brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria" [CL:0000449, GO:0050873, MESH:A.10.165.114.322]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0009118 increased white fat cell size "increase in the size of fat cells with light coloration and few mitochondria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0009132 abnormal white fat cell size "anomaly in the size of fat cells with light coloration and few mitochondria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0009133 decreased white fat cell size "reduction in the size of fat cells with light coloration and few mitochondria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf21tm1Nit/Fgf21tm1Nit
Genetic Background: C57BL/6-Fgf21tm1Nit

 MP:0009285 increased gonadal fat pad weight "greater than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0009355 increased liver triglyceride level "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0010400 increased liver glycogen level "greater than the normal concentration of a readily converted carbohydrate reserve in liver" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0011049 impaired adaptive thermogenesis "inability or reduced ability to produce heat in response to short term environmental changes, such as stress, diet or reduced temperature, often resulting in metabolic inefficiency or death" [MGI:csmith, PMID:16836744]
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Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

 MP:0011698 abnormal brown adipose tissue physiology "any functional anomaly in the thermogenic form of adipose tissue that is composed of brown adipocytes" [MGI:smb]
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Allelic Composition: Fgf21tm1Lex/Fgf21tm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6N

 MP:0011699 abnormal brown adipose tissue thermogenesis "any anomaly in the process of heat production in brown adipocytes" [MGI:smb]
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Allelic Composition: Fgf21tm1Lex/Fgf21tm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6N

 MP:0020309 increased creatine kinase activity "increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+)." [GOC:NV, PMID:18977227]
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Allelic Composition: Fgf21tm1Emf/Fgf21tm1Emf
Genetic Background: B6.Cg-Fgf21tm1Emf

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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