ENSMUSG00000031169


Mus musculus

Features
Gene ID: ENSMUSG00000031169
  
Biological name :Porcn
  
Synonyms : Porcn / Protein-serine O-palmitoleoyltransferase porcupine / Q9JJJ7
  
Possible biological names infered from orthology : porcupine O-acyltransferase / Q9H237
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A1.1
Gene start: 8193848
Gene end: 8206525
  
Corresponding Affymetrix probe sets: 10603492 (MoGene1.0st)   1424220_a_at (Mouse Genome 430 2.0 Array)   1438753_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076790
Ensembl peptide - ENSMUSP00000080937
Ensembl peptide - ENSMUSP00000086824
Ensembl peptide - ENSMUSP00000086825
Ensembl peptide - ENSMUSP00000138626
Ensembl peptide - ENSMUSP00000138661
NCBI entrez gene - 53627     See in Manteia.
MGI - MGI:1890212
RefSeq - XM_011247481
RefSeq - NM_001308474
RefSeq - NM_016913
RefSeq - NM_023638
RefSeq - NM_145907
RefSeq - NM_145908
RefSeq - XM_006527644
RefSeq - XM_006527645
RefSeq Peptide - NP_665914
RefSeq Peptide - NP_665915
RefSeq Peptide - NP_001295403
RefSeq Peptide - NP_058609
RefSeq Peptide - NP_076127
swissprot - Q9JJJ7
swissprot - S4R2F8
swissprot - S4R2I7
Ensembl - ENSMUSG00000031169
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 porcnENSDARG00000052558Danio rerio
 PORCNENSG00000102312Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004299  Membrane bound O-acyl transferase, MBOAT


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006497 protein lipidation IDA
 biological_processGO:0009100 glycoprotein metabolic process IDA
 biological_processGO:0016055 Wnt signaling pathway IMP
 biological_processGO:0045234 protein palmitoleylation IMP
 biological_processGO:0060070 canonical Wnt signaling pathway IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 cellular_componentGO:0032281 AMPA glutamate receptor complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008374 O-acyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0017147 Wnt-protein binding IPI
 molecular_functionGO:1990698 palmitoleoyltransferase activity TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Porcntm1.1Lcm/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0000414 alopecia "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Porcntm1.1Vdv/Y,Tg(KRT14-cre)1Efu/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Porcntm1Vdv/Porcn+
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Porcntm1Vdv/Y
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

 MP:0000547 short limbs "reduced average length of the extremities" [MGI:CLS, J:61509]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Porcntm1.1Vdv/Y,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J

 MP:0000564 syndactyly "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Porcntm1.1Lcm/Y,Tg(Msx2-cre)5Rem/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Porcntm1.1Vdv/Y,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J

 MP:0000565 oligodactyly "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Porcntm1Vdv/Porcn+
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Porcntm1Vdv/Y
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

 MP:0000572 abnormal autopod morphology "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Porcntm1.1Lcm/Y,Tg(Msx2-cre)5Rem/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000592 short tail "reduced length of tail compared to control " [J:55583]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
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Allelic Composition: Porcntm1.2Vdv/Porcn+
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: Porcntm1Vdv/Y
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

 MP:0001199 thin skin "reduced thickness of the outer protective layer of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]
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Allelic Composition: Porcntm1.1Vdv/Y,Tg(KRT14-cre)1Efu/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J

 MP:0001212 skin lesions "focal patches of inflammation on the skin" [J:30162]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

 MP:0001218 thin epidermis "reduced thickness of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

 MP:0001243 abnormal dermal layer morphology "malformed or atypical condition of the dermal layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:56777]
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Allelic Composition: Porcntm1.1Lcm/Y,Tg(Msx2-cre)5Rem/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001244 thin dermal layer "reduced thickness of the dermis" [J:65030]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0001247 dermal cysts "abnormal membranous sacs appearing in the dermis" [J:53379]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Porcntm1.1Lcm/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Porcntm1.1Vdv/Y,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0001680 abnormal mesoderm development "failure or abnormality in the formation of the mesoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Porcntm1.1Lcm/Porcntm1.1Lcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001696 failure to gastrulate "inability to differentiate and invaginate the primary germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:34458]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0001711 abnormal placenta 
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0001725 abnormal umbilical cord "malformed connective stalk between the fetus and the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0001726 abnormal allantois "malformed fetal membrane which contributes to the formation of the umbilical cord and placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:12622]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Porcntm1.1Vdv/Y,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J

 MP:0001924 infertility "inability to produce live offspring" [J:47225]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

 MP:0002060 abnormal skin morphology "malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0002073 abnormal hair growth "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Porcntm1Vdv/Y
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Porcntm1.1Vdv/Y,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N

Allelic Composition: Porcntm1.2Vdv/Porcn+
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N

Allelic Composition: Porcntm1.1Vdv/Porcn+,Tg(KRT14-cre)1Efu/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J

 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

 MP:0002086 abnormal extraembryonic tissue morphology "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0002100 abnormal tooth morphology "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Porcntm1.1Vdv/Y,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J

 MP:0002110 abnormal digit morphology "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

 MP:0002111 abnormal tail morphology "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Porcntm1.1Lcm/Y,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mc1rm1Btlr/Mc1rm1Btlr
Genetic Background: C57BL/6J-Mc1rm1Btlr

Allelic Composition: Porcntm1.1Lcm/Porcntm1.1Lcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Porcntm1.1Jrt/Y
Genetic Background: B6.Cg-Porcntm1.1Jrt

Allelic Composition: Porcntm1.1Jrt/Porcn+
Genetic Background: B6.Cg-Porcntm1.1Jrt

Allelic Composition: Porcntm1.1Jrt/Y
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCr * ICR

Allelic Composition: Porcntm1.1Jrt/Porcn+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCr * ICR

 MP:0002213 true hermaphroditism "having both ovarian and testicular tissue present" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

 MP:0002544 brachydactyly "abnormally short digits" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: PhexHpr/Phex+
Genetic Background: involves: C3H/HeH * C57BL/6J

Allelic Composition: Porcntm1Vdv/Y
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Porcntm1.1Vdv/Y,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J

 MP:0002759 abnormal caudal vertebrae morphology "malformed bony segments of the tail, usually 27-30 present" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:82849]
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Allelic Composition: Porcntm1Vdv/Porcn+
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Porcntm1Vdv/Y
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

 MP:0002769 abnormal vas deferens morphology "malformation of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

 MP:0003052 omphalocele "protrusion of abdominal viscera at the base of the umbilical cord, with a covering membranous sac of peritoneum-amnion" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0003384 abnormal ventral body wall "malformation in the anterior portion of a human body or the lower surface of an animal body comprised of ectoderm and mesoderm layers that encloses the body cavity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Porcntm1.1Vdv/Porcn+,Hprttm1(CAG-cre)Mnn/Hprt+
Genetic Background: involves: 129S/Sv * C57BL/6J

 MP:0003704 abnormal hair follicle development "anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Porcntm1.1Vdv/Y,Tg(KRT14-cre)1Efu/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J

 MP:0003815 nude "having no hair at some time during or throughout lifespan, generally referring to primary genetic hairlessness" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Porcntm1.1Vdv/Porcn+,Hprttm1(CAG-cre)Mnn/Hprt+
Genetic Background: involves: 129S/Sv * C57BL/6J

 MP:0004073 caudal body truncation "caudal part of body truncated with anterior portion relatively normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Porcntm1.1Vdv/Porcn+,Hprttm1(CAG-cre)Mnn/Hprt+
Genetic Background: involves: 129S/Sv * C57BL/6J

 MP:0004323 sternum hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, in the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0004360 absent ulna "missing the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0004686 decreased length of long bones "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Porcntm1.1Vdv/Y,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J

 MP:0005030 absent amnion "missing innermost of the extraembryonic membranes" [dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0008730 fused phalanges "anomaly of the long bones of the digits resulting in some or all the bones being joined together" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Relbtm1Brv/Relbtm1Brv
Genetic Background: involves: 129S2/SvPas

Allelic Composition: Porcntm1Vdv/Porcn+
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Porcntm1Vdv/Y
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

 MP:0009085 abnormal uterine horn morphology "any structural anomaly of either one of the pair of tubular extensions from the uterine body where the uterus and the uterine tubes meet; uterine horns are anterior Mullerian duct-derived structures" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Porcntm1Vdv/Porcn+
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

 MP:0009593 absent chorion "absence of the outermost extraembryonic membrane" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Porcntm1.1Lcm/Porcn+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Porcntm1.1Vdv/Porcn+,Hprttm1(CAG-cre)Mnn/Hprt+
Genetic Background: involves: 129S/Sv * C57BL/6J

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Porcntm1.2Vdv/Porcn+
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Gnl3tm2.1Rylt/Gnl3tm2.1Rylt,Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6 * CBA

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Porcntm1.1Lcm/Porcntm1.1Lcm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Porcntm1Vdv/Y
Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

Allelic Composition: Porcntm1.1Vdv/Y,Tg(EIIa-cre)C5379Lmgd/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N

Allelic Composition: Porcntm1.2Vdv/Porcn+
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N

 MP:0011102 partial embryonic lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Porcntm1.2Vdv/Porcn+
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J * FVB/N

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Porcntm1.1Vdv/Porcn+,Hprttm1(CAG-cre)Mnn/Hprt+
Genetic Background: involves: 129S/Sv * C57BL/6J

 MP:0011156 abnormal hypodermis fat layer morphology "any structural anomaly of the superficial portion of the subcutaneous tissue which is specialized for fat storage" [ISBN:0-683-40008-8]
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Allelic Composition: Porcntm1.1Vdv/Y,Tg(KRT14-cre)1Efu/0
Genetic Background: involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000009900 Wnt3a / P27467 / wingless-type MMTV integration site family, member 3A / P56704* / Wnt family member 3A*  / reaction






 

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