ENSMUSG00000031171


Mus musculus

Features
Gene ID: ENSMUSG00000031171
  
Biological name :Ftsj1
  
Synonyms : Ftsj1 / FtsJ RNA methyltransferase homolog 1
  
Possible biological names infered from orthology : Q9UET6
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A1.1
Gene start: 8238668
Gene end: 8252406
  
Corresponding Affymetrix probe sets: 10603508 (MoGene1.0st)   1417099_at (Mouse Genome 430 2.0 Array)   1430381_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121646
Ensembl peptide - ENSMUSP00000033513
Ensembl peptide - ENSMUSP00000111257
Ensembl peptide - ENSMUSP00000111258
NCBI entrez gene - 54632     See in Manteia.
MGI - MGI:1859648
RefSeq - NM_001290430
RefSeq - NM_133991
RefSeq Peptide - NP_001277359
RefSeq Peptide - NP_598752
swissprot - Q8JZY1
swissprot - A2ALH2
swissprot - Q8CBC7
swissprot - F6Q475
Ensembl - ENSMUSG00000031171
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ftsj1ENSDARG00000057089Danio rerio
 FTSJ1ENSG00000068438Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002877  Ribosomal RNA methyltransferase FtsJ domain
 IPR015507  Ribosomal RNA large subunit methyltransferase E
 IPR028590  tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001510 RNA methylation IEA
 biological_processGO:0002128 tRNA nucleoside ribose methylation IEA
 biological_processGO:0002181 cytoplasmic translation IEA
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0030488 tRNA methylation IEA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008175 tRNA methyltransferase activity IEA
 molecular_functionGO:0009020 tRNA (guanosine-2"-O-)-methyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0052666 tRNA (cytosine-2"-O-)-methyltransferase activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

Allelic Composition: Ftsj1tm1b(EUCOMM)Wtsi/Ftsj1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ftsj1tm1b(EUCOMM)Wtsi/Bay

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc12a1urehr3/Slc12a1urehr3
Genetic Background: involves: C3HeB/FeJ

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ftsj1tm1b(EUCOMM)Wtsi/Ftsj1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ftsj1tm1b(EUCOMM)Wtsi/Bay

 MP:0011965 decreased total retina thickness "decreased width of the retina through the center plane" [MGI:csmith]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/H

Allelic Composition: Ftsj1tm1b(EUCOMM)Wtsi/Ftsj1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ftsj1tm1b(EUCOMM)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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