ENSMUSG00000031239


Mus musculus

Features
Gene ID: ENSMUSG00000031239
  
Biological name :Itm2a
  
Synonyms : Integral membrane protein 2A / Itm2a / Q61500
  
Possible biological names infered from orthology : O43736
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: D
Gene start: 107397099
Gene end: 107403376
  
Corresponding Affymetrix probe sets: 10606369 (MoGene1.0st)   1423608_at (Mouse Genome 430 2.0 Array)   1451047_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033591
NCBI entrez gene - 16431     See in Manteia.
MGI - MGI:107706
RefSeq - NM_008409
RefSeq Peptide - NP_032435
swissprot - Q61500
Ensembl - ENSMUSG00000031239
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITM2AENSGALG00000004107Gallus gallus
 ITM2AENSG00000078596Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Itm2b / O89051 / Integral membrane protein 2B BRI2, membrane form BRI2 intracellular domain BRI2C, soluble form Bri23 peptide / Q9Y287* / integral membrane protein 2B*ENSMUSG0000002210841
Itm2c / Q91VK4 / Integral membrane protein 2C CT-BRI3 / Q9NQX7* / integral membrane protein 2C*ENSMUSG0000002622335


Protein motifs (from Interpro)
Interpro ID Name
 IPR007084  BRICHOS domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002317 plasma cell differentiation IMP
 biological_processGO:0002377 immunoglobulin production IMP
 biological_processGO:0007399 nervous system development IBA
 biological_processGO:0042985 negative regulation of amyloid precursor protein biosynthetic process IBA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome IBA
 molecular_functionGO:0001540 amyloid-beta binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Itm2atm1.1Buck/Y,Pax3tm1(cre)Joe/Pax3+
Genetic Background: involves: C57BL/6

Allelic Composition: Itm2atm1.2Buck/Y,Pax3tm4Buck/Pax3tm4Buck
Genetic Background: involves: C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sox4tm1Vlf/Sox4tm1Vlf,Tg(Six3-cre)69Frty/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2

Allelic Composition: Itm2atm1Buck/Itm2atm1Buck
Genetic Background: involves: C57BL/6

Allelic Composition: Itm2atm1.1Buck/Y
Genetic Background: involves: C57BL/6

Allelic Composition: Itm2atm1.1Buck/Itm2atm1.1Buck
Genetic Background: involves: C57BL/6

Allelic Composition: Itm2atm1.2Buck/Y
Genetic Background: involves: BALB/c * C57BL/6

Allelic Composition: Itm2atm1.2Buck/Itm2atm1.2Buck
Genetic Background: involves: BALB/c * C57BL/6

Allelic Composition: Itm2atm1.1Buck/Y,Pax3tm1(cre)Joe/Pax3+
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr