ENSMUSG00000031783


Mus musculus

Features
Gene ID: ENSMUSG00000031783
  
Biological name :Polr2c
  
Synonyms : DNA-directed RNA polymerase II subunit RPB3 / P97760 / Polr2c
  
Possible biological names infered from orthology : P19387 / RNA polymerase II subunit C
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C5
Gene start: 94857450
Gene end: 94873535
  
Corresponding Affymetrix probe sets: 10384349 (MoGene1.0st)   10574242 (MoGene1.0st)   1416341_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105147
Ensembl peptide - ENSMUSP00000148830
Ensembl peptide - ENSMUSP00000148434
Ensembl peptide - ENSMUSP00000148321
NCBI entrez gene - 20021     See in Manteia.
MGI - MGI:109299
RefSeq - NM_009090
RefSeq Peptide - NP_033116
swissprot - A0A1D5RLM9
swissprot - A0A1D5RLD4
swissprot - A0A1D5RML8
swissprot - P97760
Ensembl - ENSMUSG00000031783
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr2cENSDARG00000033596Danio rerio
 POLR2CENSGALG00000001168Gallus gallus
 P19387ENSG00000102978Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001514  DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
 IPR011262  DNA-directed RNA polymerase, insert domain
 IPR011263  DNA-directed RNA polymerase, RpoA/D/Rpb3-type
 IPR036603  RNA polymerase, RBP11-like subunit
 IPR036643  DNA-directed RNA polymerase, insert domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005665 DNA-directed RNA polymerase II, core complex IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 molecular_functionGO:0001055 RNA polymerase II activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Transcriptional regulation by small RNAs
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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