ENSMUSG00000031839


Mus musculus

Features
Gene ID: ENSMUSG00000031839
  
Biological name :Hsbp1
  
Synonyms : Heat shock factor-binding protein 1 / Hsbp1 / Q9CQZ1
  
Possible biological names infered from orthology : O75506
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 119344488
Gene end: 119348922
  
Corresponding Affymetrix probe sets: 10575861 (MoGene1.0st)   1423906_at (Mouse Genome 430 2.0 Array)   1451162_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034300
Ensembl peptide - ENSMUSP00000148390
NCBI entrez gene - 68196     See in Manteia.
MGI - MGI:1915446
RefSeq - NM_024219
RefSeq Peptide - NP_077181
swissprot - Q9CQZ1
Ensembl - ENSMUSG00000031839
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hsbp1bENSDARG00000041921Danio rerio
 HSBP1ENSGALG00000043039Gallus gallus
 HSBP1ENSG00000230989Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009643  Heat shock factor binding 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IEA
 biological_processGO:0035987 endodermal cell differentiation IMP
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
Attenuation phase
HSF1-dependent transactivation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001685 abnormal endoderm development "failure or abnormality in the formation of the endoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nrp1tm1.1Izac/Nrp1tm1.1Izac
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
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Allelic Composition: Nrp1tm1.1Izac/Nrp1tm1.1Izac
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031839 Hsbp1 / Q9CQZ1 / Heat shock factor-binding protein 1 / O75506*  / complex
 ENSMUSG00000022556 Hsf1 / P38532 / heat shock factor 1 / Q00613* / heat shock transcription factor 1*  / complex / reaction






 

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