ENSMUSG00000031963


Mus musculus

Features
Gene ID: ENSMUSG00000031963
  
Biological name :Bmper
  
Synonyms : BMP-binding endothelial regulator protein / Bmper / Q8CJ69
  
Possible biological names infered from orthology : BMP binding endothelial regulator / Q8N8U9
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A3
Gene start: 23223076
Gene end: 23485200
  
Corresponding Affymetrix probe sets: 10583870 (MoGene1.0st)   1429273_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000149700
Ensembl peptide - ENSMUSP00000071872
NCBI entrez gene - 73230     See in Manteia.
MGI - MGI:1920480
RefSeq - NM_028472
RefSeq Peptide - NP_082748
swissprot - A0A1L1SS01
swissprot - Q8CJ69
Ensembl - ENSMUSG00000031963
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bmperENSDARG00000101980Danio rerio
 BMPERENSGALG00000029811Gallus gallus
 BMPERENSG00000164619Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcp / Q3U492 / Kielin/chordin-like protein ENSMUSG0000005902234
Crim1 / Q9JLL0 / Cysteine-rich motor neuron 1 protein / Q9NZV1* / cysteine rich transmembrane BMP regulator 1*ENSMUSG0000002407414
Vwce / Q3U515 / von Willebrand factor C and EGF domains / Q96DN2*ENSMUSG0000004378913


Protein motifs (from Interpro)
Interpro ID Name
 IPR001007  VWFC domain
 IPR001846  von Willebrand factor, type D domain
 IPR002919  Trypsin Inhibitor-like, cysteine rich domain
 IPR014853  Uncharacterised domain, cysteine-rich
 IPR036084  Serine protease inhibitor-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001657 ureteric bud development IEP
 biological_processGO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis IEA
 biological_processGO:0010594 regulation of endothelial cell migration IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IDA
 biological_processGO:0042118 endothelial cell activation IEA
 biological_processGO:0048839 inner ear development IDA
 biological_processGO:0060393 regulation of pathway-restricted SMAD protein phosphorylation IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000030 abnormal tympanic ring morphology "malformed bony ring at the ear canal to which the tympanic membrane is attached" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]
Show

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

 MP:0000106 abnormal basisphenoid bone morphology "malformed base of the sphenoid bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
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Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

 MP:0000149 abnormal scapula morphology "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0000163 abnormal cartilage morphology "anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0000164 abnormal cartilage development "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0000592 short tail "reduced length of tail compared to control " [J:55583]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

 MP:0001176 abnormal lung development "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
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Allelic Composition: Bmpertm1Cpat/Bmper+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmp4tm2Blh/Bmp4+,Bmpertm1Ysas/Bmper+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: C57BL/6

Allelic Composition: Bmpertm1Cpat/Bmper+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
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Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0002258 abnormal cricoid cartilage morphology "any structural anomaly of the most inferior of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
Show

Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0002260 abnormal thyroid cartilage morphology "any structural anomaly of the largest of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
Show

Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0002282 abnormal trachea morphology "structral anomaly of the tube descending from the larynx and branching into the right and left main bronchi" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr

 MP:0002989 small kidney "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm1Ysas/Bmpertm1Ysas,Kcptm1Ysas/Kcptm1Ysas
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm1Ysas/Bmpertm1Ysas,Kcptm1Ysas/Kcp+
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0003051 curly tail "a loop or corkscrew-like curl in the tail" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0003120 abnormal tracheal cartilage "any structural anomaly of the cartilaginous structures that support the trachea" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:97123]
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Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr,Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0003842 abnormal metopic suture morphology "malformation of the articulation of the frontal bone from the sagital suture to the root of the nose" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]
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Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004200 reduced fetal size "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004342 scapular bone foramen "presence of a hole in either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004343 small scapula "reduced size of either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004354 absent deltoid tuberosity "missing the rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

 MP:0004384 small interparietal bone "reduced size of the bone of the cranium that lies above and anterior to the occipital bone in some mammals" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004423 abnormal squamosal bone morphology "any structural anomaly of the thin, platelike part of the temporal bone" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004444 small supraoccipital bone "reduced size of the bone on the dorsal side of the great foramen of the skull, usually forming a part of the occipital in the adult, but distinct in the young" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004463 basisphenoid bone foramen "the presence of one or more holes in part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004505 decreased renal glomerulus number "reduced number of the capillary loops of the kidney that normally function as a filtration unit" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm1Ysas/Bmpertm1Ysas,Kcptm1Ysas/Kcptm1Ysas
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm1Ysas/Bmpertm1Ysas,Kcptm1Ysas/Kcp+
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004506 abnormal pubic bone morphology "any structural anomaly in the forward portion of either of the hipbones, at the juncture forming the front arch of the pelvis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004553 absent tracheal cartilage rings "absence of the 16-20 incomplete rings of hyaline cartilage forming the skeleton of the trachea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

 MP:0004599 abnormal vertebral arch morphology "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr,Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0004603 absent vertebral arch "loss of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

 MP:0004610 small vertebrae "reduced size of the bony segments of the spinal column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

 MP:0004618 thoracic vertebral transformation "homeotic transformation of any thoracic vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr,Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0004670 small vertebral body "decreased size of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmp4tm2Blh/Bmp4+,Bmpertm1Ysas/Bmpertm1Ysas
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0004692 small pubic bone "reduced size of the forward portion of either of the hipbones, at the juncture forming the front arch of the pelvis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

 MP:0004703 abnormal vertebral column "any structural anomaly of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr,Twsg1tm1Emdr/Twsg1tm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0004915 abnormal Reichert s cartilage "any structural abnormality of the cartilage found in the mesenchyme of the second pharyngeal arch in the embryo from which develop the stapes, styloid process, lesser horn and upper part of the body of the hyoid bone; its proximal end gives rise to the stylohyoid ligament" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0005225 abnormal vertebrae development "anomalous formation of the vertebrae from the sclerotome" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0005226 abnormal vertebral arch development "anomalous formation of the posterior projection from the body of a vertebra that encloses the vertebral foramen " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmp4tm2Blh/Bmp4+,Bmpertm1Ysas/Bmpertm1Ysas
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0005227 abnormal vertebral body development "anomalous formation of the main portion of the vertebra anterior to the vertebral canal, and distinct from the vertebral arch" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmp4tm2Blh/Bmp4+,Bmpertm1Ysas/Bmpertm1Ysas
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Bmp4tm2Blh/Bmp4+,Bmpertm1Ysas/Bmper+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr,Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0009660 abnormal induced retinal neovascularization "any anomaly in the response to conditions which induce the pathological growth of vessels into the retina" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmpertm1Cpat/Bmper+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010810 increased type II pneumocyte number "greater number of the granular and roughly cuboidal cells typically found at the alveolar-septal junction that modulate the fluid surrounding the alveolar epithelium by secreting and recycling surfactants, and also contribute to tissue repair and can differentiate after injury into a type I pneumocyte; type II cells cover a much smaller surface area than type I cells (less than 5 percent), but are much more numerous and contain lamellar bodies on the apical surface where surfactant is stored" [ISBN:0412046911, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", PMID:8540632]
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Allelic Composition: Bmpertm1Cpat/Bmper+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010825 abnormal lung saccule morphology "any structural anomaly of the transient dilations of the developing alveolar (or transient) ducts, which transform into a transitory alveolar duct as soon as it develops further branches; the last transitory saccule formed on each pathway is a terminal saccule that develops into an alveolar sac after birth" [GO:0060430, ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmpertm1Cpat/Bmper+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010827 small lung saccule "reduced size of the transient dilations of the developing alveolar (or transient) ducts, which transform into a transitory alveolar duct as soon as it develops further branches; the last transitory saccule formed on each pathway is a terminal saccule that develops into an alveolar sac after birth" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bmpertm1Cpat/Bmper+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011024 abnormal branching involved in lung morphogenesis "anomaly in the process in which the branched structure of the respiratory airway tree is generated and organized" [MGI:csmith]
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Allelic Composition: Bmpertm1Cpat/Bmper+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr
Genetic Background: B6SJL-Bmpertm1Emdr

Allelic Composition: Bmpertm1Cpat/Bmpertm1Cpat
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Bmpertm1Emdr/Bmper+,Twsg1tm1Emdr/Twsg1tm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0011143 thick lung-associated mesenchyme "increased thickness of the mesenchymal cell layer due to delay or failure of the mesenchymal compartment to thin down during the late stages of embryonic lung development" [MGI:anna]
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Allelic Composition: Bmpertm1Cpat/Bmper+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011290 decreased nephron number "reduction in the total number of filtering units of the kidney" [MGI:anna]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

Allelic Composition: Bmpertm2Ysas/Bmpertm2Ysas
Genetic Background: involves: C57BL/6 * CBA

 MP:0011376 abnormal kidney corticomedullary boundary morphology "any structural anomaly of the region demarcating the renal medulla from the surrounding cortex; end-stage renal failure may be associated with loss of the normal corticomedullary boundary" [MGI:anna]
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Allelic Composition: Bmpertm1Ysas/Bmpertm1Ysas,Kcptm1Ysas/Kcptm1Ysas
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Bmpertm1Ysas/Bmpertm1Ysas,Kcptm1Ysas/Kcp+
Genetic Background: involves: C57BL/6 * CBA

 MP:0030120 absent retrotympanic process "absence of the posterior extension of the squamosal bone that normally lies just above the incus" [MGI:anna, PMID:28566723]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

 MP:0030431 wide metopic suture "an abnormally increased width of the metopic suture for age-related norms" [MGI:anna]
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Allelic Composition: Plgtm1Jld/Plgtm1Jld
Genetic Background: involves: 129P2/OlaHsd * Black Swiss * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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