ENSMUSG00000031979


Mus musculus

Features
Gene ID: ENSMUSG00000031979
  
Biological name :Cog2
  
Synonyms : Cog2 / Conserved oligomeric Golgi complex subunit 2 / Q921L5
  
Possible biological names infered from orthology : component of oligomeric golgi complex 2 / Q14746
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E2
Gene start: 124520767
Gene end: 124552008
  
Corresponding Affymetrix probe sets: 10576439 (MoGene1.0st)   1416932_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135600
Ensembl peptide - ENSMUSP00000034460
Ensembl peptide - ENSMUSP00000135022
NCBI entrez gene - 76332     See in Manteia.
MGI - MGI:1923582
RefSeq - NM_029746
RefSeq Peptide - NP_084022
swissprot - Q921L5
swissprot - H3BJK5
swissprot - H3BL04
Ensembl - ENSMUSG00000031979
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cog2ENSDARG00000004037Danio rerio
 COG2ENSGALG00000011114Gallus gallus
 COG2ENSG00000135775Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009316  COG complex component, COG2
 IPR024602  Conserved oligomeric Golgi complex, subunit 2, N-terminal
 IPR024603  COG complex component, COG2, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IEA
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0017119 Golgi transport complex IEA
 molecular_functionGO:0008565 protein transporter activity IEA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport
Intra-Golgi traffic
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0002608 increased hematocrit "greater than average percentage of a volume of a blood sample occupied by red blood cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0002942 decreased circulating alanine transaminase level "decreased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0005554 decreased circulating creatinine level "less than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0005571 decreased lactate dehydrogenase level "less than the normal concentration of this enzyme, which catalyzes the interconversion of lactate and pyruvate" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

 MP:0005632 decreased circulating aspartate transaminase level "less than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr