| MP:0000547 | short limbs | "reduced average length of the extremities" [MGI:CLS, J:61509] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
|
| MP:0000852 | small cerebellum | "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0000857 | abnormal cerebellar foliation | "malformation of small offshoots of the cerebellar lobules" [Principles of Neural Science:ISBN 0-8385-8034-3, J:52951] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0000877 | abnormal Purkinje cell | "any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
|
| MP:0000920 | abnormal myelination | "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0001127 | small ovary | "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0001289 | persistence of hyaloid capillary system | "failure of the degeneration of the transient vascular system of the eye during development" [J:49840] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0001304 | cataracts | "complete or partial opacity of the lens" [J:65031] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
|
| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
|
| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0002118 | abnormal lipid homeostasis | "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
|
| MP:0002175 | low brain weight | "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0002216 | abnormal seminiferous tubule morphology | "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
|
| MP:0002427 | dwarfism | "abnormally undersized with disproportionate body parts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0002794 | lenticonus | "a conical bulging of the lens capsule and the underlying cortex of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0005159 | azoospermia | "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0005201 | abnormal retinal pigment epithelium morphology | "anomaly in the epithelial layer of the retina composed of cells containing pigment granules " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0005205 | abnormal eye anterior chamber | "anomaly of the space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0006221 | optic nerve hypoplasia | "less than the normal number of fibers in the optic nerve" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0008261 | arrest of male meiosis | "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0008540 | abnormal cerebrum morphology | "any structural anomaly of the largest part of the brain, derived from the telencephalon, and is composed of a right and a left hemisphere each which contains an outer cerebral cortex and a subcortical basal ganglia; cerebral functions include sensorimotor, emotional, and intellectual activities" [MESH:A08.186.211.730.885.287] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0008814 | reduced nerve conduction velocity | "decrease in the rate at which an eletrical impulse travels through a nerve" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0009977 | abnormal cerebellar granule cell migration | "defective or impaired movement of cerebellar granule cell neurons from the germinal zone into the granule cell layer of the cerebellum during development of the cerebellar cortex" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0010734 | abnormal paranode morphology | "any structural anomaly of the axon region immediately adjacent to nodes of Ranvier, where a series of cytoplasmic loops from the overlying glial cell form septate-like junctions with the axon; the axoglial junctions act as a diffusion barrier between the node and internode" [PMID:16224497] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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| MP:0010735 | abnormal paranodal axoglial junction morphology | "any structural anomaly of the structure in which the myelin sheath attaches to the axon at each end of each myelin segment; the axoglial junctions act as a diffusion barrier between the node and internode, maintaining domain-specific axolemmal membrane components" [PMID:19224642] |
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Allelic Composition: Roratmgc26/Roratmgc26
Genetic Background: involves: D7R75M
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