ENSMUSG00000032494


Mus musculus

Features
Gene ID: ENSMUSG00000032494
  
Biological name :Tdgf1
  
Synonyms : Tdgf1 / teratocarcinoma-derived growth factor 1
  
Possible biological names infered from orthology : P13385
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F2
Gene start: 110939603
Gene end: 110946158
  
Corresponding Affymetrix probe sets: 10597268 (MoGene1.0st)   1450989_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035075
Ensembl peptide - ENSMUSP00000143669
Ensembl peptide - ENSMUSP00000143394
Ensembl peptide - ENSMUSP00000142397
NCBI entrez gene - 21667     See in Manteia.
MGI - MGI:98658
RefSeq - NM_011562
RefSeq Peptide - NP_035692
swissprot - A0A0G2JG22
swissprot - A0A0G2JDJ9
swissprot - A0A0G2JGR6
swissprot - Q7TQ06
Ensembl - ENSMUSG00000032494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tdgf1ENSDARG00000035095Danio rerio
 TDGF1ENSG00000241186Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cfc1 / P97766 / Cryptic protein / CFC1B* / P0CG36* / P0CG37* / cripto, FRL-1, cryptic family 1* / cripto, FRL-1, cryptic family 1B*ENSMUSG0000002612430


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR013032  EGF-like, conserved site
 IPR017047  Teratocarcinoma-derived growth factor Cripto
 IPR019011  Cryptic/Cripto, CFC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0002042 cell migration involved in sprouting angiogenesis IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0035729 cellular response to hepatocyte growth factor stimulus IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 biological_processGO:0071354 cellular response to interleukin-6 IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tdgf1tm1.1Gmin/Tdgf1tm1.1Gmin
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000267 abnormal cardiac development "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0000932 absent notochord "missing axial fibrocellular cord in embryos around which develops the vertebral primordia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:12622]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001674 abnormal triploblastic development "abnormal development of the three primary germ layers" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

 MP:0001680 abnormal mesoderm development "failure or abnormality in the formation of the mesoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6)

 MP:0001683 absent mesoderm "missing or failure to differentiate the middle primary germ layer " [J:40594]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

 MP:0001685 abnormal endoderm development "failure or abnormality in the formation of the endoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001693 failure of primitive streak formation "inability to form the epiblast ridge from which arises the germ layers of the embryo" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:33880]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

 MP:0001695 abnormal gastrulation "anomalous development and invagination of the embryonic germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

Allelic Composition: Tdgf1tm1.1Gmin/Tdgf1tm1.1Gmin
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6)

 MP:0001700 abnormal embryo turning "atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (Mus:E8.5-E9.5) such that the curvature of the entire trunk region is reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tdgf1tm1.1Gmin/Tdgf1tm1.1Gmin
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001719 absent vitelline blood vessels "missing vasculature of the yolk sac" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62571, J:12623]
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Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
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Allelic Composition: Tdgf1tm1.1Gmin/Tdgf1tm1.1Gmin
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6)

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0002084 abnormal developmental patterning "abnormal systematic arrangement of the developing body along an axis" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Grid2tm1(cre/PGR)Ksak/Grid2tm1(cre/PGR)Ksak
Genetic Background: C57BL/6-Grid2tm1(cre/PGR)Ksak

Allelic Composition: Tdgf1tm1.1Gmin/Tdgf1tm1.1Gmin
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Grid2tm1(cre/PGR)Ksak/Grid2tm1(cre/PGR)Ksak
Genetic Background: C57BL/6-Grid2tm1(cre/PGR)Ksak

Allelic Composition: Tdgf1tm1.1Gmin/Tdgf1tm1.1Gmin
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002086 abnormal extraembryonic tissue morphology "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Grid2tm1(cre/PGR)Ksak/Grid2tm1(cre/PGR)Ksak
Genetic Background: C57BL/6-Grid2tm1(cre/PGR)Ksak

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mecp2tm1.1Vnar/Mecp2tm1.1Vnar
Genetic Background: B6N.129-Mecp2tm1.1Vnar

 MP:0002230 abnormal primitive streak formation "anomaly in the establishment of the midline ridge of embryonic epiblast that later develops into mesoderm and endoderm" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6)

 MP:0002836 abnormal chorion "malformations of the outermost extraembryonic membrane" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0003566 abnormal cell adhesion "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0004261 abnormal embryonic neuroepithelium morphology "any structural anomaly in the epithelial cell layer that lines the neural tube and develops into the nervous system and into the neural crest cells" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition", MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0004388 absent prechordal plate "absence of the horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann s organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0005029 abnormal amnion "malformed innermost layer of the extraembryonic membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0005157 holoprosencephaly "presence of a single forebrain hemisphere or lobe; often accompanied by a deficit in median facial development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83058]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0005163 cyclopia "a congenital defect in which the two orbits are united to form a single cavity containing one eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60303]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0005221 abnormal rostral-caudal axis patterning "anomaly in the development or formation of the axis that runs from the head to the tail of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

Allelic Composition: Cer1tm1Belo/Cer1tm1Belo,Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0006386 absent somites "missing all somites" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

Allelic Composition: Tdgf1tm1.1Gmin/Tdgf1tm1.1Gmin
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009266 abnormal mesendoderm development "failure or abnormality in the formation of the embryonic cell layer that gives rise to both the endoderm and mesoderm" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

Allelic Composition: Tdgf1tm1.1Gmin/Tdgf1tm1.1Gmin
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011186 abnormal visceral endoderm morphology "any structural anomaly of the primitive endoderm-derived tissue which remains in contact with and surrounds the extra-embryonic ectoderm and the epiblast and provides signals for the differentiation and patterning of the epiblast; a small number of visceral endoderm cells also contribute to the endoderm of the embryonic gut" [PMID:21123814]
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Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Genetic Background: B6.129-Bcl2l11tm1.1Ast Baxtm1Sjk

 MP:0011204 abnormal visceral yolk sac blood island morphology "any structural anomaly of the masses of developing blood cells attached to endothelium in the yolk sac" [PMID:16140152]
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Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0011256 abnormal neural fold morphology "any structural anomaly of the elevated margins of the neural groove" [ISBN:0-683-40008-8]
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Allelic Composition: Tdgf1tm1.1Gmin/Tdgf1tm1.1Gmin
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011704 decreased fibroblast proliferation "reduction in the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
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Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0011733 fused somites "a defect in which there is an appearance of a single enlarged somite resulting from partial or complete fusion of the two somitic anlage" [MGI:smb]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0012089 decreased midbrain size "size reduction or truncation of the brain region derived from the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions in the adult, including eye movement and coordination of auditory and visual reflexes" [MGI:anna, MGI:csmith]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0012138 decreased forebrain size "size reduction or truncation of the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)" [GO:0048853]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0012157 rostral body truncation "rostral part of body truncated; typically with the caudal portion of the body relatively normal" [MGI:csmith]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0012173 short rostral-caudal axis "length reduction or truncation of the axis that runs from the head to the tail of the body" [MGI:anna]
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Allelic Composition: Tdgf1tm1Eda/Tdgf1tm1Eda
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)

 MP:0013185 absent anterior definitive endoderm "absence of the mesendoderm which first migrates from the node and which gives rise to the gut" [MGI:anna]
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Allelic Composition: Cdx2tm1Fbe/Cdx2+,Cdx4tm1.1Jdes/Cdx4+
Genetic Background: involves: 129 * C57BL/6 * CBA * FVB

Allelic Composition: Tdgf1tm2Mms/Tdgf1tm2.1Mms
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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