ENSMUSG00000032602


Mus musculus

Features
Gene ID: ENSMUSG00000032602
  
Biological name :Slc25a20
  
Synonyms : Q9Z2Z6 / Slc25a20 / solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
  
Possible biological names infered from orthology : O43772 / solute carrier family 25 member 20
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F2
Gene start: 108662088
Gene end: 108684641
  
Corresponding Affymetrix probe sets: 10589076 (MoGene1.0st)   1423108_at (Mouse Genome 430 2.0 Array)   1423109_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035222
NCBI entrez gene - 57279     See in Manteia.
MGI - MGI:1928738
RefSeq - NM_020520
RefSeq Peptide - NP_065266
swissprot - Q9Z2Z6
Ensembl - ENSMUSG00000032602
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc25a20ENSDARG00000040401Danio rerio
 SLC25A20ENSGALG00000028227Gallus gallus
 O43772ENSG00000178537Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8CFJ7 / Slc25a45 / Solute carrier family 25 member 45 / Q8N413*ENSMUSG0000002481835
Q8BL03 / Slc25a29 / solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29 / Q8N8R3* / solute carrier family 25 member 29*ENSMUSG0000002126534
Q6IS41 / Slc25a47 / Solute carrier family 25 member 47 / Q6Q0C1*ENSMUSG0000004885633
Q8BW66 / Slc25a48 / Solute carrier family 25 member 48 / Q6ZT89*ENSMUSG0000002150932


Protein motifs (from Interpro)
Interpro ID Name
 IPR018108  Mitochondrial substrate/solute carrier
 IPR023395  Mitochondrial carrier domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006839 mitochondrial transport IBA
 biological_processGO:0015879 carnitine transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1902603 carnitine transmembrane transport IEA
 biological_processGO:1902616 acyl carnitine transmembrane transport IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005476 carnitine:acyl carnitine antiporter activity IBA
 molecular_functionGO:0015226 carnitine transmembrane transporter activity IBA
 molecular_functionGO:0015227 acyl carnitine transmembrane transporter activity ISO


Pathways (from Reactome)
Pathway description
Import of palmitoyl-CoA into the mitochondrial matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001785 edema "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0003826 abnormal Mullerian duct morphology "malformation of the transient embryonic tubes that empty into the cloaca and in the female develop into the oviducts, uterus, and vagina" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0005633 increased circulating sodium level "greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0010530 cerebral arteriovenous malformation "congenital vascular anomaly in the cerebrum characterized by direct communication between an artery and a vein without passing through the capillary bed" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0010912 herniated liver "protrusion of any portion of the liver from its normal anatomical position" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0011493 double ureter "two ureters open separately into the renal pelvis superiorly and drain separately into the urinary bladder or genital tract; if two ureteral buds arise from the Wolffian duct, a duplex kidney with complete ureteral duplication ensues" [http://emedicine.medscape.com/article/378075-overview, MGI:anna]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0012303 umbilical vein stenosis "abnormal constriction or narrowing of the unpaired umbilical vein that carries oxygenated, nutrient-rich blood from the placenta to the fetus" [MGI:anna]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0013842 ductus venosus stenosis "narrowing of the lumen of the embryonic connection between the portal vein and inferior vena cava formed by the left umbilical vein that allows oxygenated blood to bypass the developing liver during the time when this connection is normally open; this normally closes during develpment to adulthood" [MGI:csmith]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0013847 retropleural edema "accumulation of watery or serous fluid in the retropleural space" [MGI:csmith]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0013851 abnormal Wolffian duct topology "aberrant postition of the transient embryonic drainage tubes of the embryonic kidney (mesonephric tubules) that empty into the cloaca and later develop into the ductus deferens in the male" [ISBN:0-683-40008-8]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0013865 abnormal dorsal pancreas topology "aberrant location or orientation of the transient embryonic structure that fuses with the ventral pancreas during development to form a single organ" [PMID:23909279]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0013963 jugular vein stenosis 
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0013968 multiple persisting craniopharyngeal ducts 
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0013986 abnormal vitelline vein topology "abnormal position of the paired veins that carry blood from the yolk sac back to the embryo" [MGI:csmith]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0014019 embryo cyst 
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1l+
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr