ENSMUSG00000032890


Mus musculus

Features
Gene ID: ENSMUSG00000032890
  
Biological name :Rims3
  
Synonyms : Q80U57 / regulating synaptic membrane exocytosis 3 / Rims3
  
Possible biological names infered from orthology : Q9UJD0
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D2.2
Gene start: 120854816
Gene end: 120896579
  
Corresponding Affymetrix probe sets: 10507731 (MoGene1.0st)   1435971_at (Mouse Genome 430 2.0 Array)   1459042_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000068178
Ensembl peptide - ENSMUSP00000101890
Ensembl peptide - ENSMUSP00000130295
NCBI entrez gene - 242662     See in Manteia.
MGI - MGI:2443331
RefSeq - XM_006503102
RefSeq - NM_182929
RefSeq - XM_006503101
RefSeq Peptide - NP_891559
swissprot - Q80U57
swissprot - Q14BY7
Ensembl - ENSMUSG00000032890
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rims3ENSDARG00000062305Danio rerio
 RIMS3ENSGALG00000003174Gallus gallus
 RIMS3ENSG00000117016Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rims2 / Q9EQZ7 / Regulating synaptic membrane exocytosis protein 2 / Q9UQ26* / regulating synaptic membrane exocytosis 2*ENSMUSG0000003738668
Rims1 / regulating synaptic membrane exocytosis 1 / Q86UR5*ENSMUSG0000004167066
Rims4 / P60191 / Regulating synaptic membrane exocytosis protein 4 / Q9H426* / regulating synaptic membrane exocytosis 4*ENSMUSG0000003522650


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0017156 calcium ion regulated exocytosis ISS
 biological_processGO:0042391 regulation of membrane potential IDA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 biological_processGO:2000300 regulation of synaptic vesicle exocytosis IBA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048786 presynaptic active zone IBA
 molecular_functionGO:0044325 ion channel binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003020 decreased circulating chloride level "reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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