ENSMUSG00000033066


Mus musculus

Features
Gene ID: ENSMUSG00000033066
  
Biological name :Gas7
  
Synonyms : Gas7 / growth arrest-specific protein 7 isoform d
  
Possible biological names infered from orthology : growth arrest specific 7 / O60861
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 67455437
Gene end: 67688990
  
Corresponding Affymetrix probe sets: 10377215 (MoGene1.0st)   1417859_at (Mouse Genome 430 2.0 Array)   1431400_a_at (Mouse Genome 430 2.0 Array)   1445685_at (Mouse Genome 430 2.0 Array)   1457270_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038420
Ensembl peptide - ENSMUSP00000104320
Ensembl peptide - ENSMUSP00000104321
Ensembl peptide - ENSMUSP00000104322
NCBI entrez gene - 14457     See in Manteia.
MGI - MGI:1202388
RefSeq - XM_017314262
RefSeq - NM_001109657
RefSeq - NM_001277079
RefSeq - NM_001277080
RefSeq - NM_008088
RefSeq - XM_006532202
RefSeq - XM_006532205
RefSeq - XM_006532208
RefSeq - XM_006532209
RefSeq - XM_006532210
RefSeq - XM_006532211
RefSeq Peptide - NP_001103127
RefSeq Peptide - NP_001264008
RefSeq Peptide - NP_001264009
RefSeq Peptide - NP_032114
swissprot - Q3U432
swissprot - B1ATI9
Ensembl - ENSMUSG00000033066
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01102038.1ENSDARG00000116210Danio rerio
 gas7aENSDARG00000074443Danio rerio
 GAS7ENSGALG00000032452Gallus gallus
 GAS7ENSG00000007237Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pstpip1 / proline-serine-threonine phosphatase interacting protein 1 / O43586*ENSMUSG0000003232214
Q99M15 / Pstpip2 / Proline-serine-threonine phosphatase-interacting protein 2 / Q9H939*ENSMUSG0000002542913


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR001202  WW domain
 IPR027267  AH/BAR domain superfamily
 IPR031160  F-BAR domain
 IPR036020  WW domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000748 progressive muscle weakness "increasing loss of strength over time" [MGI:CLS, J:67994]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0000939 reduced motor neuron number "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0003081 abnormal soleus morphology "anomaly in the the superficial flat broad muscle of the calf that is responsible for plantar flexion of the foot" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, smb:Susan M. Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0004243 abnormal motor nerve terminal sprouting "aberrant response of a motor neuron to form new neuritic processes (sprouts) that emerge from the nodes of Ranvier or terminal arborizations in response to nerve injury (such as denervation), application of nerve toxin, or muscle inactivity (usually due to disease)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0009401 increased skeletal muscle fiber diameter "increased width of the cross-sectional distance that extends from one lateral edge of a skeletal muscle fiber, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0009409 abnormal skeletal muscle fiber type ratio "deviation from the standard ratios of fiber types in a given skeletal muscle compared to control samples" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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