ENSMUSG00000032322


Mus musculus

Features
Gene ID: ENSMUSG00000032322
  
Biological name :Pstpip1
  
Synonyms : proline-serine-threonine phosphatase interacting protein 1 / Pstpip1
  
Possible biological names infered from orthology : O43586
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: B
Gene start: 56089962
Gene end: 56128888
  
Corresponding Affymetrix probe sets: 10585555 (MoGene1.0st)   1424560_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055823
NCBI entrez gene - 19200     See in Manteia.
MGI - MGI:1321396
RefSeq - XM_011242677
RefSeq - NM_011193
RefSeq - XM_006510867
RefSeq - XM_006510868
RefSeq - XM_006510865
RefSeq - XM_006510866
RefSeq Peptide - NP_035323
swissprot - A0A0R4J0P5
Ensembl - ENSMUSG00000032322
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pstpip1aENSDARG00000060860Danio rerio
 pstpip1bENSDARG00000053568Danio rerio
 PSTPIP1ENSGALG00000002786Gallus gallus
 O43586ENSG00000140368Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q99M15 / Pstpip2 / Proline-serine-threonine phosphatase-interacting protein 2 / Q9H939*ENSMUSG0000002542934
Gas7 / growth arrest-specific protein 7 isoform d / O60861* / growth arrest specific 7*ENSMUSG0000003306614


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR027267  AH/BAR domain superfamily
 IPR030777  PSTPIP1, SH3 domain
 IPR031160  F-BAR domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
The NLRP3 inflammasome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000716 abnormal immune system cell morphology "anomalous structure, development, or number of immune cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Shhtm1(cre/ERT2)Tshim/Shhtm1(cre/ERT2)Tshim
Genetic Background: Not Specified

 MP:0002444 abnormal T cell physiology "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Shhtm1(cre/ERT2)Tshim/Shhtm1(cre/ERT2)Tshim
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022534 Mefv / Pyrin / Q9JJ26 / O15553* / MEFV, pyrin innate immunity regulator*  / complex / reaction
 ENSMUSG00000032322 Pstpip1 / proline-serine-threonine phosphatase interacting protein 1 / O43586*  / complex






 

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contact: otassy@igbmc.fr