ENSMUSG00000033170


Mus musculus

Features
Gene ID: ENSMUSG00000033170
  
Biological name :Card10
  
Synonyms : Card10 / Caspase recruitment domain-containing protein 10 / P58660
  
Possible biological names infered from orthology : caspase recruitment domain family member 10 / Q9BWT7
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E1
Gene start: 78775138
Gene end: 78803042
  
Corresponding Affymetrix probe sets: 10430400 (MoGene1.0st)   1449491_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000131003
Ensembl peptide - ENSMUSP00000129513
NCBI entrez gene - 105844     See in Manteia.
MGI - MGI:2146012
RefSeq - NM_130859
RefSeq - XM_006520253
RefSeq Peptide - NP_570929
swissprot - E9PUV9
swissprot - P58660
Ensembl - ENSMUSG00000033170
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01040998.1ENSDARG00000111638Danio rerio
 CARD10ENSGALG00000042365Gallus gallus
 CARD10ENSG00000100065Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Card11 / Q8CIS0 / Caspase recruitment domain-containing protein 11 / Q9BXL7* / caspase recruitment domain family member 11*ENSMUSG0000003652636
Card14 / Q99KF0 / Caspase recruitment domain-containing protein 14 / Q9BXL6* / caspase recruitment domain family member 14*ENSMUSG0000001348324
Card9 / A2AIV8 / Caspase recruitment domain-containing protein 9 / Q9H257* / caspase recruitment domain family member 9*ENSMUSG0000002692818


Protein motifs (from Interpro)
Interpro ID Name
 IPR001315  CARD domain
 IPR011029  Death-like domain superfamily
 IPR034660  DinB/YfiT-like putative metalloenzymes


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity ISS
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0090051 negative regulation of cell migration involved in sprouting angiogenesis IEA
 biological_processGO:1900182 positive regulation of protein localization to nucleus IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001890 anencephaly "absence of the bones of the cranial vault and absent or rudimentary cerebral and cerebellar hemispheres, brainstem, and basal ganglia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:31571]
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Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tg(HLA-A/H2-D/B2M)1Dvs/0
Genetic Background: NOD.Cg-B2mtm1Unc Tg(HLA-A/H2-D/B2M)1Dvs

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tg(HLA-A/H2-D/B2M)1Dvs/0
Genetic Background: NOD.Cg-B2mtm1Unc Tg(HLA-A/H2-D/B2M)1Dvs

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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