ENSMUSG00000033970


Mus musculus

Features
Gene ID: ENSMUSG00000033970
  
Biological name :Rfc3
  
Synonyms : Q8R323 / replication factor C (activator 1) 3 / Rfc3
  
Possible biological names infered from orthology : P40938 / replication factor C subunit 3
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G3
Gene start: 151642756
Gene end: 151651242
  
Corresponding Affymetrix probe sets: 10535979 (MoGene1.0st)   1423700_at (Mouse Genome 430 2.0 Array)   1432538_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039621
NCBI entrez gene - 69263     See in Manteia.
MGI - MGI:1916513
RefSeq - NM_027009
RefSeq Peptide - NP_081285
swissprot - Q3TKD1
swissprot - Q8R323
Ensembl - ENSMUSG00000033970
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rfc3ENSDARG00000055969Danio rerio
 RFC3ENSGALG00000017064Gallus gallus
 RFC3ENSG00000133119Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR008921  DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication ISO
 biological_processGO:0006261 DNA-dependent DNA replication IBA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0046683 response to organophosphorus IEA
 biological_processGO:1900264 positive regulation of DNA-directed DNA polymerase activity IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005663 DNA replication factor C complex ISO
 cellular_componentGO:0031390 Ctf18 RFC-like complex IEA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003689 DNA clamp loader activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0043142 single-stranded DNA-dependent ATPase activity IEA


Pathways (from Reactome)
Pathway description
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Polymerase switching on the C-strand of the telomere
Activation of ATR in response to replication stress
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Regulation of TP53 Activity through Phosphorylation
Polymerase switching
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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