ENSMUSG00000034371


Mus musculus

Features
Gene ID: ENSMUSG00000034371
  
Biological name :Tkfc
  
Synonyms : Q8VC30 / Tkfc / Triokinase/FMN cyclase ATP-dependent dihydroxyacetone kinase FAD-AMP lyase (cyclizing)
  
Possible biological names infered from orthology : Q3LXA3 / triokinase and FMN cyclase
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 10592200
Gene end: 10604258
  
Corresponding Affymetrix probe sets: 10466008 (MoGene1.0st)   1425300_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000044556
NCBI entrez gene - 225913     See in Manteia.
MGI - MGI:2385084
RefSeq - XM_011247223
RefSeq - NM_145496
RefSeq - XM_006526943
RefSeq - XM_006526944
RefSeq - XM_006526941
RefSeq - XM_006526942
RefSeq Peptide - NP_663471
swissprot - Q8VC30
Ensembl - ENSMUSG00000034371
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tkfcENSDARG00000062085Danio rerio
 TKFCENSGALG00000037854Gallus gallus
 TKFCENSG00000149476Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004006  DhaK domain
 IPR004007  DhaL domain
 IPR012734  Dihydroxyacetone kinase
 IPR036117  DhaL domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006071 glycerol metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0039534 negative regulation of MDA-5 signaling pathway IEA
 biological_processGO:0044262 cellular carbohydrate metabolic process IEA
 biological_processGO:0045088 regulation of innate immune response IEA
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 biological_processGO:0061624 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate IC
 biological_processGO:0061625 glycolytic process through fructose-1-phosphate IC
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004371 glycerone kinase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0034012 FAD-AMP lyase (cyclizing) activity ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050354 triokinase activity ISO


Pathways (from Reactome)
Pathway description
Fructose catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000034371 Tkfc / Q8VC30 / Triokinase/FMN cyclase ATP-dependent dihydroxyacetone kinase FAD-AMP lyase (cyclizing) / Q3LXA3* / triokinase and FMN cyclase*  / complex






 

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